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1TR5

Room temperature structure of Staphylococcal nuclease variant truncated Delta+PHS I92E

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0004518molecular_functionnuclease activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE CA A 301
ChainResidue
AASP21
AASP40
ATHR41
AGLU43
ATHP300

site_idAC2
Number of Residues13
DetailsBINDING SITE FOR RESIDUE THP A 300
ChainResidue
AARG87
ALEU89
ATYR113
ALYS127
AHOH203
AHOH204
AHOH211
AHOH212
ACA301
AARG35
AASP40
ALYS84
ATYR85

Functional Information from PROSITE/UniProt
site_idPS01123
Number of Residues25
DetailsTNASE_1 Thermonuclease family signature 1. DGDTVkLmykgqpmtf.RLllVDtPE
ChainResidueDetails
AASP19-GLU43

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:288045
ChainResidueDetails
AARG35
AGLU43
ATYR93

site_idSWS_FT_FI2
Number of Residues3
DetailsBINDING:
ChainResidueDetails
AASP21
AASP40
ATHR41

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1a2t
ChainResidueDetails
AARG35
AARG87

site_idMCSA1
Number of Residues6
DetailsM-CSA 165
ChainResidueDetails
AASP21metal ligand
AARG35electrostatic stabiliser, hydrogen bond donor
AASP40metal ligand
ATHR41metal ligand
AGLU43hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
ATYR93electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

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PDB entries from 2024-10-30

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