1TQM

Crystal Structure of A. fulgidus Rio2 Serine Protein Kinase Bound to AMPPNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004672	molecular_function	protein kinase activity
A	0004674	molecular_function	protein serine/threonine kinase activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006468	biological_process	protein phosphorylation
A	0030490	biological_process	maturation of SSU-rRNA
A	0030688	cellular_component	preribosome, small subunit precursor
A	0046872	molecular_function	metal ion binding
A	0106310	molecular_function	protein serine kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	BINDING SITE FOR RESIDUE ANP A 283

Chain	Residue
A	MET98
A	ASN223
A	ILE234
A	ASP235
A	HOH284
A	HOH313
A	HOH340
A	HOH368
A	HOH375
A	HOH398
A	HOH405
A	GLU103
A	HOH423
A	HOH443
A	HOH461
A	SER104
A	LYS120
A	MET179
A	GLU180
A	ILE182
A	GLU186
A	TYR222

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Functional Information from PROSITE/UniProt

site_id	PS00109
Number of Residues	13
Details	PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. IVHgDLSQYNVLV

Chain	Residue	Details
A	ILE214-VAL226

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	ASP218

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159

Chain	Residue	Details
A	MET98

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site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305|PubMed:15943813

Chain	Residue	Details
A	GLU103
A	ASN223
A	ASP235

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:15341724

Chain	Residue	Details
A	LYS120

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site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:15943813, ECO:0007744|PDB:1ZAO

Chain	Residue	Details
A	HIS126

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site_id	SWS_FT_FI6
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:15341724, ECO:0000269|PubMed:15943813, ECO:0007744|PDB:1TQP, ECO:0007744|PDB:1ZAO

Chain	Residue	Details
A	GLU180

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site_id	SWS_FT_FI7
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:15341724, ECO:0007744|PDB:1TQP

Chain	Residue	Details
A	TYR222

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site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphoserine; by autocatalysis => ECO:0000269|PubMed:15943813

Chain	Residue	Details
A	SER128

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 2phk

Chain	Residue	Details
A	ASP218
A	SER220

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