1TQD

Crystal structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000045	biological_process	autophagosome assembly
A	0000166	molecular_function	nucleotide binding
A	0002376	biological_process	immune system process
A	0003924	molecular_function	GTPase activity
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005794	cellular_component	Golgi apparatus
A	0009617	biological_process	response to bacterium
A	0010506	biological_process	regulation of autophagy
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0019003	molecular_function	GDP binding
A	0019221	biological_process	cytokine-mediated signaling pathway
A	0020005	cellular_component	symbiont-containing vacuole membrane
A	0031965	cellular_component	nuclear membrane
A	0032580	cellular_component	Golgi cisterna membrane
A	0035458	biological_process	cellular response to interferon-beta
A	0042802	molecular_function	identical protein binding
A	0042832	biological_process	defense response to protozoan
A	0045087	biological_process	innate immune response
A	0050829	biological_process	defense response to Gram-negative bacterium
B	0000045	biological_process	autophagosome assembly
B	0000166	molecular_function	nucleotide binding
B	0002376	biological_process	immune system process
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005794	cellular_component	Golgi apparatus
B	0009617	biological_process	response to bacterium
B	0010506	biological_process	regulation of autophagy
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0019003	molecular_function	GDP binding
B	0019221	biological_process	cytokine-mediated signaling pathway
B	0020005	cellular_component	symbiont-containing vacuole membrane
B	0031965	cellular_component	nuclear membrane
B	0032580	cellular_component	Golgi cisterna membrane
B	0035458	biological_process	cellular response to interferon-beta
B	0042802	molecular_function	identical protein binding
B	0042832	biological_process	defense response to protozoan
B	0045087	biological_process	innate immune response
B	0050829	biological_process	defense response to Gram-negative bacterium

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 B 1000

Chain	Residue
B	GLY79
B	SER80
B	GLY81
B	LYS82
B	SER83
B	SER84
B	THR102
B	LYS184
B	HOH2269

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MES B 2000

Chain	Residue
B	SER35
B	GLU64
B	ILE253
B	TYR254
B	HOH2073
B	HOH2257

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12732635","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25118287","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LV5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LV8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25118287","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LV5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4LV8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12732635","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"25118287","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LV5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	4
Details	Modified residue: {"description":"(Microbial infection) Phosphothreonine; by ROP18","evidences":[{"source":"PubMed","id":"21203588","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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