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1TQ4

Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0002376biological_processimmune system process
A0003924molecular_functionGTPase activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0005794cellular_componentGolgi apparatus
A0006952biological_processdefense response
A0009617biological_processresponse to bacterium
A0010506biological_processregulation of autophagy
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0019003molecular_functionGDP binding
A0019221biological_processcytokine-mediated signaling pathway
A0020005cellular_componentsymbiont-containing vacuole membrane
A0031965cellular_componentnuclear membrane
A0032580cellular_componentGolgi cisterna membrane
A0035458biological_processcellular response to interferon-beta
A0042802molecular_functionidentical protein binding
A0042832biological_processdefense response to protozoan
A0045087biological_processinnate immune response
A0050829biological_processdefense response to Gram-negative bacterium
A0098542biological_processdefense response to other organism
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 501
ChainResidue
ALYS82
ASER83
AASP126
AGDP500
AHOH927

site_idAC2
Number of Residues21
DetailsBINDING SITE FOR RESIDUE GDP A 500
ChainResidue
ALYS82
ASER83
ASER84
ATHR102
AGLY103
ALYS184
AASP186
ASER231
AASN232
ALYS233
AMG501
AHOH743
AHOH775
AHOH795
AHOH893
AHOH929
AHOH930
AGLU77
AGLY79
ASER80
AGLY81

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:12732635
ChainResidueDetails
AGLY79
AGLY81
ALYS82
ASER83
AGLY103
ALYS184
AASP186
AASN232

site_idSWS_FT_FI2
Number of Residues1
DetailsLIPID: N-myristoyl glycine => ECO:0000305
ChainResidueDetails
AGLY2

218853

PDB entries from 2024-04-24

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