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1TQ2

Crystal Structure of IIGP1: a paradigm for interferon inducible p47 resistance GTPases

Functional Information from GO Data
ChainGOidnamespacecontents
A0003924molecular_functionGTPase activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005783cellular_componentendoplasmic reticulum
A0005789cellular_componentendoplasmic reticulum membrane
A0005794cellular_componentGolgi apparatus
A0009617biological_processresponse to bacterium
A0010506biological_processregulation of autophagy
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0019003molecular_functionGDP binding
A0019221biological_processcytokine-mediated signaling pathway
A0020005cellular_componentsymbiont-containing vacuole membrane
A0031965cellular_componentnuclear membrane
A0032580cellular_componentGolgi cisterna membrane
A0035458biological_processcellular response to interferon-beta
A0042802molecular_functionidentical protein binding
A0042832biological_processdefense response to protozoan
A0045087biological_processinnate immune response
A0050829biological_processdefense response to Gram-negative bacterium
B0003924molecular_functionGTPase activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005783cellular_componentendoplasmic reticulum
B0005789cellular_componentendoplasmic reticulum membrane
B0005794cellular_componentGolgi apparatus
B0009617biological_processresponse to bacterium
B0010506biological_processregulation of autophagy
B0016020cellular_componentmembrane
B0016787molecular_functionhydrolase activity
B0019003molecular_functionGDP binding
B0019221biological_processcytokine-mediated signaling pathway
B0020005cellular_componentsymbiont-containing vacuole membrane
B0031965cellular_componentnuclear membrane
B0032580cellular_componentGolgi cisterna membrane
B0035458biological_processcellular response to interferon-beta
B0042802molecular_functionidentical protein binding
B0042832biological_processdefense response to protozoan
B0045087biological_processinnate immune response
B0050829biological_processdefense response to Gram-negative bacterium
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MG B 1501
ChainResidue
BSER83
BASP126
BGNP1500

site_idAC2
Number of Residues17
DetailsBINDING SITE FOR RESIDUE GNP A 500
ChainResidue
ASER83
ASER84
ATHR102
AGLY103
AVAL104
ALYS184
AASP186
AASN232
ALYS233
AHOH501
BGLU335
AGLU77
ATHR78
AGLY79
ASER80
AGLY81
ALYS82

site_idAC3
Number of Residues18
DetailsBINDING SITE FOR RESIDUE GNP B 1500
ChainResidue
AGLU97
BTHR78
BGLY79
BSER80
BGLY81
BLYS82
BSER83
BSER84
BGLY103
BTHR108
BLYS184
BASP186
BSER187
BSER231
BASN232
BLYS233
BMG1501
BHOH1502

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MPD B 1000
ChainResidue
BILE38
BGLU64
BILE253
BTYR254
BHOH1566

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues16
DetailsBINDING: BINDING => ECO:0000269|PubMed:12732635
ChainResidueDetails
AGLY79
BGLY81
BLYS82
BSER83
BGLY103
BLYS184
BASP186
BASN232
AGLY81
ALYS82
ASER83
AGLY103
ALYS184
AASP186
AASN232
BGLY79

site_idSWS_FT_FI2
Number of Residues2
DetailsLIPID: N-myristoyl glycine => ECO:0000305
ChainResidueDetails
AGLY2
BGLY2

226707

PDB entries from 2024-10-30

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