1TPY
Structure of the cyclopropane synthase MmaA2 from Mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008610 | biological_process | lipid biosynthetic process |
| A | 0008825 | molecular_function | cyclopropane-fatty-acyl-phospholipid synthase activity |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0071768 | biological_process | mycolic acid biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE CO3 A 902 |
| Chain | Residue |
| A | SER34 |
| A | CYS35 |
| A | GLY137 |
| A | GLU140 |
| A | HIS167 |
| A | THR168 |
| A | ILE169 |
| A | TYR232 |
| A | 16A1901 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE SAH A 1900 |
| Chain | Residue |
| A | VAL12 |
| A | TYR16 |
| A | THR32 |
| A | TYR33 |
| A | SER34 |
| A | GLY72 |
| A | GLY74 |
| A | THR94 |
| A | LEU95 |
| A | SER96 |
| A | GLN99 |
| A | GLY122 |
| A | TRP123 |
| A | GLU124 |
| A | ILE136 |
| A | GLY137 |
| A | ALA138 |
| A | HIS141 |
| A | PHE142 |
| A | 16A1901 |
| A | HOH1902 |
| A | HOH1905 |
| A | HOH1928 |
| A | HOH1932 |
| A | HOH1946 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 16A A 1901 |
| Chain | Residue |
| A | TYR16 |
| A | TYR33 |
| A | GLY137 |
| A | GLU140 |
| A | HIS141 |
| A | ILE169 |
| A | ILE195 |
| A | PHE200 |
| A | PRO205 |
| A | TYR232 |
| A | LEU236 |
| A | CYS269 |
| A | CO3902 |
| A | SAH1900 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2004","submissionDatabase":"EMBL/GenBank/DDBJ databases","title":"Structure of the cyclopropane synthase mmaA2 from Mycobacterium tuberculosis.","authors":["Smith C.V.","Sacchettini J.C."]}}]} |
| Chain | Residue | Details |
