1TOP

STRUCTURE OF CHICKEN SKELETAL MUSCLE TROPONIN-C AT 1.78 ANGSTROMS RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003009	biological_process	skeletal muscle contraction
A	0005509	molecular_function	calcium ion binding
A	0005861	cellular_component	troponin complex
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 163

Chain	Residue
A	ASP106
A	ASN108
A	ASP110
A	PHE112
A	GLU117
A	HOH176

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 164

Chain	Residue
A	ARG148
A	GLU153
A	HOH209
A	ASP142
A	ASN144
A	ASP146

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 225

Chain	Residue
A	GLY43
A	ARG47
A	LYS55
A	HOH230
A	HOH234
A	HOH240
A	HOH254
A	HOH306

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DADGGGDIStkEL

Chain	Residue	Details
A	ASP30-LEU42
A	ASP66-PHE78
A	ASP106-LEU118
A	ASP142-PHE154

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	35
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	35
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	33
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Blocked amino end (Ala)"}

Chain

Residue

Details

---