Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0015035 | molecular_function | protein-disulfide reductase activity |
Functional Information from PDB Data
| site_id | ACT |
| Number of Residues | 5 |
| Details | SSBOND AT REDOX-ACTIVE CENTER. |
| Chain | Residue |
| A | TRP35 |
| A | CYS36 |
| A | GLY37 |
| A | PRO38 |
| A | CYS39 |
Functional Information from PROSITE/UniProt
| site_id | PS00194 |
| Number of Residues | 19 |
| Details | THIOREDOXIN_1 Thioredoxin family active site. VVdFTatWCGPCKmIaplF |
| Chain | Residue | Details |
| A | VAL28-PHE46 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 110 |
| Details | Domain: {"description":"Thioredoxin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00691","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Deprotonates C-terminal active site Cys"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Contributes to redox potential value"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| A | PRO38 | |
| A | CYS39 | |
| A | GLY37 | |
| A | CYS36 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| A | CYS39 | |
| A | CYS36 | |
