1TO5
Structure of the cytosolic Cu,Zn SOD from S. mansoni
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004784 | molecular_function | superoxide dismutase activity |
| A | 0005507 | molecular_function | copper ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006801 | biological_process | superoxide metabolic process |
| A | 0016209 | molecular_function | antioxidant activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019430 | biological_process | removal of superoxide radicals |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004784 | molecular_function | superoxide dismutase activity |
| B | 0005507 | molecular_function | copper ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006801 | biological_process | superoxide metabolic process |
| B | 0016209 | molecular_function | antioxidant activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019430 | biological_process | removal of superoxide radicals |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| C | 0004784 | molecular_function | superoxide dismutase activity |
| C | 0005507 | molecular_function | copper ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006801 | biological_process | superoxide metabolic process |
| C | 0016209 | molecular_function | antioxidant activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019430 | biological_process | removal of superoxide radicals |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0098869 | biological_process | cellular oxidant detoxification |
| D | 0004784 | molecular_function | superoxide dismutase activity |
| D | 0005507 | molecular_function | copper ion binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006801 | biological_process | superoxide metabolic process |
| D | 0016209 | molecular_function | antioxidant activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019430 | biological_process | removal of superoxide radicals |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 711 |
| Chain | Residue |
| A | HIS62 |
| A | HIS70 |
| A | HIS79 |
| A | ASP82 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU A 712 |
| Chain | Residue |
| A | HIS45 |
| A | HIS47 |
| A | HIS62 |
| A | HIS119 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 721 |
| Chain | Residue |
| B | HIS70 |
| B | HIS79 |
| B | ASP82 |
| B | HIS62 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU B 722 |
| Chain | Residue |
| B | HIS45 |
| B | HIS47 |
| B | HIS62 |
| B | HIS119 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 731 |
| Chain | Residue |
| C | HIS62 |
| C | HIS70 |
| C | HIS79 |
| C | ASP82 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU C 732 |
| Chain | Residue |
| C | HIS45 |
| C | HIS47 |
| C | HIS62 |
| C | HIS119 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 741 |
| Chain | Residue |
| D | HIS62 |
| D | HIS70 |
| D | HIS79 |
| D | ASP82 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CU D 742 |
| Chain | Residue |
| D | HIS45 |
| D | HIS47 |
| D | HIS62 |
| D | HIS119 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 701 |
| Chain | Residue |
| B | GLU22 |
| B | HIS29 |
| B | HOH832 |
| C | GLN68 |
| C | HOH822 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | HIS45 | |
| D | HIS45 | |
| D | HIS47 | |
| D | HIS119 | |
| A | HIS47 | |
| A | HIS119 | |
| B | HIS45 | |
| B | HIS47 | |
| B | HIS119 | |
| C | HIS45 | |
| C | HIS47 | |
| C | HIS119 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15333927 |
| Chain | Residue | Details |
| A | HIS62 | |
| C | HIS70 | |
| C | HIS79 | |
| C | ASP82 | |
| D | HIS62 | |
| D | HIS70 | |
| D | HIS79 | |
| D | ASP82 | |
| A | HIS70 | |
| A | HIS79 | |
| A | ASP82 | |
| B | HIS62 | |
| B | HIS70 | |
| B | HIS79 | |
| B | ASP82 | |
| C | HIS62 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2jcw |
| Chain | Residue | Details |
| A | ARG142 | |
| A | HIS62 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2jcw |
| Chain | Residue | Details |
| B | ARG142 | |
| B | HIS62 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2jcw |
| Chain | Residue | Details |
| C | ARG142 | |
| C | HIS62 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2jcw |
| Chain | Residue | Details |
| D | ARG142 | |
| D | HIS62 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2jcw |
| Chain | Residue | Details |
| A | HIS62 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2jcw |
| Chain | Residue | Details |
| B | HIS62 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2jcw |
| Chain | Residue | Details |
| C | HIS62 |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2jcw |
| Chain | Residue | Details |
| D | HIS62 |
