1TMX
Crystal structure of hydroxyquinol 1,2-dioxygenase from Nocardioides Simplex 3E
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0008199 | molecular_function | ferric iron binding |
A | 0009056 | biological_process | catabolic process |
A | 0009712 | biological_process | catechol-containing compound metabolic process |
A | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
A | 0018576 | molecular_function | catechol 1,2-dioxygenase activity |
A | 0018581 | molecular_function | hydroxyquinol 1,2-dioxygenase activity |
A | 0042952 | biological_process | beta-ketoadipate pathway |
A | 0046872 | molecular_function | metal ion binding |
A | 0047074 | molecular_function | 4-hydroxycatechol 1,2-dioxygenase activity |
A | 0051213 | molecular_function | dioxygenase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0005506 | molecular_function | iron ion binding |
B | 0008199 | molecular_function | ferric iron binding |
B | 0009056 | biological_process | catabolic process |
B | 0009712 | biological_process | catechol-containing compound metabolic process |
B | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
B | 0018576 | molecular_function | catechol 1,2-dioxygenase activity |
B | 0018581 | molecular_function | hydroxyquinol 1,2-dioxygenase activity |
B | 0042952 | biological_process | beta-ketoadipate pathway |
B | 0046872 | molecular_function | metal ion binding |
B | 0047074 | molecular_function | 4-hydroxycatechol 1,2-dioxygenase activity |
B | 0051213 | molecular_function | dioxygenase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FE A 861 |
Chain | Residue |
A | TYR164 |
A | TYR197 |
A | HIS221 |
A | HIS223 |
A | BEZ881 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FE B 862 |
Chain | Residue |
B | BEZ882 |
B | TYR164 |
B | TYR197 |
B | HIS221 |
B | HIS223 |
site_id | AC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE CU A 871 |
Chain | Residue |
A | HIS42 |
A | CL891 |
B | HIS42 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL A 891 |
Chain | Residue |
A | HIS42 |
A | CU871 |
A | HOH1072 |
B | HIS42 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 901 |
Chain | Residue |
B | THR53 |
B | ALA55 |
B | HOH987 |
B | HOH1050 |
B | HOH1112 |
B | HOH1264 |
site_id | AC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 902 |
Chain | Residue |
A | LYS255 |
A | ASP256 |
A | SER257 |
A | HOH941 |
A | HOH1160 |
A | HOH1207 |
site_id | AC7 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE HGX A 851 |
Chain | Residue |
A | PHE46 |
A | GLY60 |
A | PHE63 |
A | MET208 |
A | HOH1112 |
B | VAL35 |
B | HGX852 |
site_id | AC8 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE HGX B 852 |
Chain | Residue |
A | LEU32 |
A | HGX851 |
B | GLU56 |
B | TRP57 |
B | THR59 |
B | PHE63 |
B | ALA211 |
B | HOH1284 |
B | HOH1297 |
site_id | AC9 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE BEZ A 881 |
Chain | Residue |
A | LEU80 |
A | ASP83 |
A | GLY109 |
A | PRO110 |
A | PHE111 |
A | TYR197 |
A | ILE199 |
A | ARG218 |
A | HIS221 |
A | HIS223 |
A | FE861 |
A | HOH908 |
site_id | BC1 |
Number of Residues | 12 |
Details | BINDING SITE FOR RESIDUE BEZ B 882 |
Chain | Residue |
B | ASP83 |
B | GLY109 |
B | PRO110 |
B | PHE111 |
B | TYR197 |
B | ILE199 |
B | ARG218 |
B | HIS221 |
B | HIS223 |
B | VAL251 |
B | FE862 |
B | HOH948 |
Functional Information from PROSITE/UniProt
site_id | PS00083 |
Number of Residues | 29 |
Details | INTRADIOL_DIOXYGENAS Intradiol ring-cleavage dioxygenases signature. VeGtVtdtdGnpVpdarIEVweadddGfY |
Chain | Residue | Details |
A | VAL136-TYR164 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 8 |
Details | BINDING: BINDING => ECO:0000269|PubMed:15772073 |
Chain | Residue | Details |
A | TYR164 | |
A | TYR197 | |
A | HIS221 | |
A | HIS223 | |
B | TYR164 | |
B | TYR197 | |
B | HIS221 | |
B | HIS223 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 3pca |
Chain | Residue | Details |
A | ARG218 | |
A | TYR197 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 3pca |
Chain | Residue | Details |
B | ARG218 | |
B | TYR197 |