Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1TKP

Iron-oxo clusters biomineralizing on protein surfaces. Structural analysis of H.salinarum DpsA in its low and high iron states

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
B	0005737	cellular_component	cytoplasm
B	0006879	biological_process	intracellular iron ion homeostasis
B	0008199	molecular_function	ferric iron binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
C	0005737	cellular_component	cytoplasm
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008199	molecular_function	ferric iron binding
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
D	0005737	cellular_component	cytoplasm
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008199	molecular_function	ferric iron binding
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 401

Chain	Residue
A	HIS150
A	ARG153
C	HIS150
C	ARG153
D	HIS150
D	ARG153

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 B 402

Chain	Residue
B	ARG153
B	ARG153
B	ARG153
B	HIS150
B	HIS150
B	HIS150

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE D 301

Chain	Residue
C	HIS52
D	ASP79
D	GLU83
D	HOH383

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE D 302

Chain	Residue
C	ASP79
C	GLU83
C	HOH563
D	HIS52

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE B 303

Chain	Residue
A	HIS52
B	ASP79
B	GLU83
B	HOH443
B	HOH456

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 304

Chain	Residue
A	ASP79
A	GLU83
A	HOH550
B	HIS52
B	HOH457

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FE B 305

Chain	Residue
B	GLU154
B	GLU154
B	GLU154
B	FE322
B	FE322
B	FE322
B	HOH458
B	HOH458
B	HOH458

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE C 306

Chain	Residue
A	FE307
A	FE308
A	FE313
A	FE321
C	GLU154
C	HOH564
C	HOH565

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 307

Chain	Residue
A	GLU154
A	FE308
A	FE313
A	FE321
A	HOH551
C	FE306
C	HOH564

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 308

Chain	Residue
A	FE307
A	FE313
A	FE321
A	HOH551
C	FE306
C	HOH565
D	GLU154

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE D 309

Chain	Residue
A	HIS168
C	GLN86
D	GLU56

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE A 310

Chain	Residue
A	HIS164
A	HIS168
C	GLN86
D	TRP53

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE C 311

Chain	Residue
C	GLU75
D	GLU75
D	FE312
D	FE323

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE D 312

Chain	Residue
C	GLU75
C	FE311
D	GLU75
D	FE323

site_id	BC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FE A 313

Chain	Residue
A	GLU154
A	FE307
A	FE308
A	HOH551
C	GLU154
C	FE306
C	HOH564
C	HOH565
D	GLU154

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE D 314

Chain	Residue
C	GLU56
C	HIS168
D	GLN86

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 315

Chain	Residue
A	GLU75
A	FE316
A	FE324
A	HOH527
B	GLU75

site_id	BC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 316

Chain	Residue
A	GLU75
A	FE315
A	FE324
B	GLU72
B	GLU75

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE B 317

Chain	Residue
B	HIS168
A	GLU56
B	GLN86

site_id	CC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE B 318

Chain	Residue
A	GLN86
B	GLU56
D	HIS168

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FE D 319

Chain	Residue
C	GLU171
C	ASP172

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE B 320

Chain	Residue
B	FE322
B	FE322
B	FE322
B	HOH450

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE A 321

Chain	Residue
A	FE307
A	FE308
C	FE306

site_id	CC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FE B 322

Chain	Residue
B	GLU154
B	FE305
B	FE305
B	FE305
B	FE320
B	FE320
B	FE320
B	HOH450
B	HOH458
B	HOH458

site_id	CC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE D 323

Chain	Residue
C	GLU75
C	FE311
D	GLU72
D	GLU75
D	FE312

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FE A 324

Chain	Residue
A	FE315
A	FE316

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE D 325

Chain	Residue
C	HIS164
D	GLU83
D	GLN86

site_id	DC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FE B 326

Chain	Residue
B	GLU83
B	HIS164

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE B 327

Chain	Residue
B	TRP53
B	HOH453
D	HIS164
D	HIS168

site_id	DC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FE A 328

Chain	Residue
D	ASP172

site_id	DC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FE B 329

Chain	Residue
B	GLU171
B	HOH411

site_id	DC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FE A 330

Chain	Residue
A	ASP172

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 501

Chain	Residue
A	GLU59
B	GLU59
D	GLU59

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA C 502

Chain	Residue
C	GLU59
C	GLU59
C	GLU59

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269\|PubMed:15365182

Chain	Residue	Details
A	HIS52
B	HIS52
C	HIS52
D	HIS52

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: in other chain => ECO:0000269\|PubMed:15365182

Chain	Residue	Details
A	ASP79
B	ASP79
C	ASP79
D	ASP79

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLU83
B	GLU83
C	GLU83
D	GLU83

site_id	SWS_FT_FI4
Number of Residues	28
Details	SITE: Involved in iron translocation

Chain	Residue	Details
A	TRP53
B	VAL85
B	GLN86
B	HIS164
B	HIS168
B	GLU171
C	TRP53
C	GLU56
C	VAL85
C	GLN86
C	HIS164
A	GLU56
C	HIS168
C	GLU171
D	TRP53
D	GLU56
D	VAL85
D	GLN86
D	HIS164
D	HIS168
D	GLU171
A	VAL85
A	GLN86
A	HIS164
A	HIS168
A	GLU171
B	TRP53
B	GLU56

site_id	SWS_FT_FI5
Number of Residues	8
Details	SITE: Involved in iron nucleation

Chain	Residue	Details
A	GLU75
A	GLU154
B	GLU75
B	GLU154
C	GLU75
C	GLU154
D	GLU75
D	GLU154

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)