Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1TKO

Iron-oxo clusters biomineralizing on protein surfaces. Structural analysis of H.salinarum DpsA in its low and high iron states

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
B	0005737	cellular_component	cytoplasm
B	0006879	biological_process	intracellular iron ion homeostasis
B	0008199	molecular_function	ferric iron binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
C	0005737	cellular_component	cytoplasm
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008199	molecular_function	ferric iron binding
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
D	0005737	cellular_component	cytoplasm
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008199	molecular_function	ferric iron binding
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 201

Chain	Residue
A	HIS150
A	ARG153
C	HIS150
C	ARG153
D	HIS150
D	ARG153
D	HOH502

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 202

Chain	Residue
B	HIS150
B	ARG153
B	ARG153
B	HOH338
B	HOH338
B	HOH338
B	HIS150
B	HIS150

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE B 301

Chain	Residue
B	GLU154
B	GLU154
B	GLU154
B	FE319
B	FE321

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE FE A 302

Chain	Residue
A	GLU154
A	FE304
A	HOH346
C	GLU154
C	FE303
C	FE309
D	GLU154

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE C 303

Chain	Residue
A	FE302
A	FE304
A	FE320
C	GLU154
C	FE309

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 304

Chain	Residue
A	GLU154
A	FE302
A	FE320
A	HOH346
C	FE303

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE C 305

Chain	Residue
A	HIS168
C	GLN86
D	GLU56

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE A 306

Chain	Residue
A	HIS164
A	HIS168
C	GLN86
D	TRP53

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FE C 307

Chain	Residue
C	FE308
C	FE324

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE C 308

Chain	Residue
C	GLU75
C	FE307
C	FE324
D	GLU75

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE C 309

Chain	Residue
A	FE302
A	FE320
A	HOH346
C	FE303
D	GLU154

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE D 310

Chain	Residue
C	GLU56
C	HIS168
D	GLN86

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE B 311

Chain	Residue
A	GLU75
A	FE312
A	FE325
A	HOH348
B	GLU75

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 312

Chain	Residue
A	GLU75
A	FE325
B	GLU72
B	GLU75
B	FE311

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE B 313

Chain	Residue
A	GLU56
B	GLN86
B	HIS168

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE A 314

Chain	Residue
A	GLN86
B	GLU56
D	HIS168

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE D 315

Chain	Residue
C	GLU171
C	ASP172
D	ASP25
D	HOH506

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FE A 316

Chain	Residue
A	GLU80
A	GLU83

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE C 317

Chain	Residue
C	GLU80
C	GLU83
C	FE329
C	HOH508

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FE B 318

Chain	Residue
B	GLU80
B	GLU83

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FE B 319

Chain	Residue
B	FE301
B	FE321

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE A 320

Chain	Residue
A	FE304
C	FE303
C	FE309

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE B 321

Chain	Residue
B	GLU154
B	FE301
B	FE319

site_id	CC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FE A 322

Chain	Residue
A	ASP172

site_id	CC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FE D 323

Chain	Residue
D	GLU80

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE C 324

Chain	Residue
D	GLU75
C	GLU75
C	FE307
C	FE308

site_id	CC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE A 325

Chain	Residue
A	FE312
A	HOH348
B	FE311

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE D 326

Chain	Residue
C	HIS52
D	ASP79
D	GLU83
D	FE327

site_id	DC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE D 327

Chain	Residue
C	HIS64
D	GLU83
D	FE326

site_id	DC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE C 328

Chain	Residue
C	ASP79
C	GLU83
C	FE329
D	HIS52

site_id	DC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE C 329

Chain	Residue
C	GLU83
C	FE317
C	FE328
D	HIS64

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE FE B 330

Chain	Residue
A	HIS52
B	ASP79
B	GLU83
B	FE331

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE B 331

Chain	Residue
A	HIS64
B	GLU83
B	FE330

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE A 332

Chain	Residue
A	ASP79
A	GLU83
B	HIS52

site_id	DC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FE B 333

Chain	Residue
B	HIS64

site_id	DC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FE C 334

Chain	Residue
C	TRP53

site_id	EC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE B 335

Chain	Residue
B	TRP53
D	HIS164
D	HIS168

site_id	EC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FE B 336

Chain	Residue
B	GLU15
B	GLU171
B	HOH341

site_id	EC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FE A 338

Chain	Residue
A	TRP53
A	HIS64

site_id	EC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA D 501

Chain	Residue
A	GLU59
D	GLU59

site_id	EC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA C 502

Chain	Residue
C	ALA58
C	GLU59
C	GLU59

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269\|PubMed:15365182

Chain	Residue	Details
A	HIS52
B	HIS52
C	HIS52
D	HIS52

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: in other chain => ECO:0000269\|PubMed:15365182

Chain	Residue	Details
A	ASP79
B	ASP79
C	ASP79
D	ASP79

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLU83
B	GLU83
C	GLU83
D	GLU83

site_id	SWS_FT_FI4
Number of Residues	28
Details	SITE: Involved in iron translocation

Chain	Residue	Details
A	TRP53
B	VAL85
B	GLN86
B	HIS164
B	HIS168
B	GLU171
C	TRP53
C	GLU56
C	VAL85
C	GLN86
C	HIS164
A	GLU56
C	HIS168
C	GLU171
D	TRP53
D	GLU56
D	VAL85
D	GLN86
D	HIS164
D	HIS168
D	GLU171
A	VAL85
A	GLN86
A	HIS164
A	HIS168
A	GLU171
B	TRP53
B	GLU56

site_id	SWS_FT_FI5
Number of Residues	8
Details	SITE: Involved in iron nucleation

Chain	Residue	Details
A	GLU75
A	GLU154
B	GLU75
B	GLU154
C	GLU75
C	GLU154
D	GLU75
D	GLU154

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)