1TKJ

Streptomyces griseus aminopeptidase complexed with D-Methionine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0006508	biological_process	proteolysis
A	0008235	molecular_function	metalloexopeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 901

Chain	Residue
A	HIS85
A	ASP97
A	ASP160
A	ZN902
A	MED913

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 902

Chain	Residue
A	MED913
A	ASP97
A	GLU132
A	HIS247
A	ZN901

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 905

Chain	Residue
A	ASP3
A	ILE4
A	ASP262
A	ASP266
A	HOH1447
A	HOH1448

---

site_id	AC4
Number of Residues	19
Details	BINDING SITE FOR RESIDUE MED A 913

Chain	Residue
A	HIS85
A	ASP97
A	GLU131
A	GLU132
A	ASP160
A	MET161
A	TYR172
A	GLU198
A	GLY199
A	ASP200
A	ARG202
A	HIS205
A	PHE219
A	ALA222
A	TYR246
A	HIS247
A	ZN901
A	ZN902
A	HOH1469

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"15280041","evidenceCode":"ECO:0000303"},{"source":"PubMed","id":"17608735","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15388919","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9048953","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"15280041","evidenceCode":"ECO:0000303"},{"source":"PubMed","id":"17608735","evidenceCode":"ECO:0000303"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1amp

Chain	Residue	Details
A	GLU131

---