1TIY
X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0006144 | biological_process | purine nucleobase metabolic process |
| A | 0006147 | biological_process | guanine catabolic process |
| A | 0006152 | biological_process | purine nucleoside catabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008892 | molecular_function | guanine deaminase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047974 | molecular_function | guanosine deaminase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0006144 | biological_process | purine nucleobase metabolic process |
| B | 0006147 | biological_process | guanine catabolic process |
| B | 0006152 | biological_process | purine nucleoside catabolic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008892 | molecular_function | guanine deaminase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047974 | molecular_function | guanosine deaminase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 200 |
| Chain | Residue |
| A | HIS53 |
| A | CYS83 |
| A | CYS86 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 201 |
| Chain | Residue |
| B | HIS53 |
| B | GLU55 |
| B | CYS83 |
| B | CYS86 |
| B | HOH226 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 38 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAEvtAIrkackvlgayqlddcilytsce...........PCpm......ClgaI |
| Chain | Residue | Details |
| A | HIS53-ILE90 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU55 | |
| B | GLU55 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | HIS53 | |
| A | CYS83 | |
| A | CYS86 | |
| B | HIS53 | |
| B | CYS83 | |
| B | CYS86 |
