1TGX
X-RAY STRUCTURE AT 1.55 A OF TOXIN GAMMA, A CARDIOTOXIN FROM NAJA NIGRICOLLIS VENOM. CRYSTAL PACKING REVEALS A MODEL FOR INSERTION INTO MEMBRANES
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0044218 | cellular_component | other organism cell membrane |
| A | 0090729 | molecular_function | toxin activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0044218 | cellular_component | other organism cell membrane |
| B | 0090729 | molecular_function | toxin activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0031640 | biological_process | killing of cells of another organism |
| C | 0035821 | biological_process | modulation of process of another organism |
| C | 0044218 | cellular_component | other organism cell membrane |
| C | 0090729 | molecular_function | toxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 102 |
| Chain | Residue |
| A | LYS12 |
| A | LYS18 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 120 |
| Chain | Residue |
| A | LEU1 |
| A | LEU1 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 102 |
| Chain | Residue |
| B | LYS12 |
| B | CL106 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 106 |
| Chain | Residue |
| B | CL102 |
| B | LYS12 |
| B | GLY37 |
| B | CYS38 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 120 |
| Chain | Residue |
| B | LEU1 |
| B | LYS2 |
| C | LEU1 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 123 |
| Chain | Residue |
| A | HOH291 |
| B | ARG36 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 102 |
| Chain | Residue |
| C | LYS12 |
| C | PRO15 |
| C | LYS18 |
| C | CL106 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL C 106 |
| Chain | Residue |
| C | LYS12 |
| C | CYS38 |
| C | CL102 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL C 113 |
| Chain | Residue |
| A | LYS44 |
| B | TRP11 |
| C | PRO43 |
| C | LYS44 |
| C | HOH151 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 206 |
| Chain | Residue |
| B | LYS16 |
| C | LYS16 |
| C | HOH150 |
| site_id | BC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 242 |
| Chain | Residue |
| A | ARG36 |
| C | LYS50 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 245 |
| Chain | Residue |
| A | ARG27 |
| A | HOH288 |
| A | HOH292 |
| A | HOH304 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 260 |
| Chain | Residue |
| A | ARG27 |
| A | HOH304 |
| C | ARG27 |
| site_id | BC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 270 |
| Chain | Residue |
| B | LYS18 |
Functional Information from PROSITE/UniProt
| site_id | PS00272 |
| Number of Residues | 21 |
| Details | SNAKE_TOXIN Snake toxins signature. GCidvCPkssllikym.CCntD |
| Chain | Residue | Details |
| A | GLY37-ASP57 |
