1TFW

How CCA is added to the 3' end of immature tRNA without the use of an oligonucleotide template

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0001680	biological_process	tRNA 3'-terminal CCA addition
A	0003723	molecular_function	RNA binding
A	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
A	0005524	molecular_function	ATP binding
A	0008033	biological_process	tRNA processing
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0031123	biological_process	RNA 3'-end processing
A	0042245	biological_process	RNA repair
A	0046872	molecular_function	metal ion binding
A	0106354	biological_process	tRNA surveillance
A	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity
B	0000049	molecular_function	tRNA binding
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0001680	biological_process	tRNA 3'-terminal CCA addition
B	0003723	molecular_function	RNA binding
B	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
B	0005524	molecular_function	ATP binding
B	0008033	biological_process	tRNA processing
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0031123	biological_process	RNA 3'-end processing
B	0042245	biological_process	RNA repair
B	0046872	molecular_function	metal ion binding
B	0106354	biological_process	tRNA surveillance
B	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity
C	0000049	molecular_function	tRNA binding
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0001680	biological_process	tRNA 3'-terminal CCA addition
C	0003723	molecular_function	RNA binding
C	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
C	0005524	molecular_function	ATP binding
C	0008033	biological_process	tRNA processing
C	0016740	molecular_function	transferase activity
C	0016779	molecular_function	nucleotidyltransferase activity
C	0031123	biological_process	RNA 3'-end processing
C	0042245	biological_process	RNA repair
C	0046872	molecular_function	metal ion binding
C	0106354	biological_process	tRNA surveillance
C	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity
D	0000049	molecular_function	tRNA binding
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0001680	biological_process	tRNA 3'-terminal CCA addition
D	0003723	molecular_function	RNA binding
D	0004810	molecular_function	CCA tRNA nucleotidyltransferase activity
D	0005524	molecular_function	ATP binding
D	0008033	biological_process	tRNA processing
D	0016740	molecular_function	transferase activity
D	0016779	molecular_function	nucleotidyltransferase activity
D	0031123	biological_process	RNA 3'-end processing
D	0042245	biological_process	RNA repair
D	0046872	molecular_function	metal ion binding
D	0106354	biological_process	tRNA surveillance
D	0160016	molecular_function	CCACCA tRNA nucleotidyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 1601

Chain	Residue
B	SER47
B	GLU59
B	ASP61
B	ATP1501

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 1602

Chain	Residue
D	GLU59
D	ASP61
D	ATP1502

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ATP B 1501

Chain	Residue
B	ARG50
B	GLU59
B	ASP61
B	THR130
B	HIS133
B	LYS152
B	TYR161
B	ARG224
B	MG1601
B	HOH1647
B	HOH1685
H	A73
H	C74
H	C75
B	GLY46
B	SER47

---

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ATP D 1502

Chain	Residue
D	GLY46
D	SER47
D	ARG50
D	GLU59
D	ASP61
D	THR130
D	HIS133
D	LYS152
D	TYR161
D	ARG224
D	MG1602
D	HOH1675
D	HOH1753
D	HOH1767
I	A73
I	C74
I	C75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14636575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25640237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"14636575","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25640237","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4Q","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4X4S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1UEV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14592988","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1R89","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1UEV","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---