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1TFP

TRANSTHYRETIN (FORMERLY KNOWN AS PREALBUMIN)

Functional Information from GO Data
ChainGOidnamespacecontents
A0001555biological_processoocyte growth
A0005179molecular_functionhormone activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006144biological_processpurine nucleobase metabolic process
A0007165biological_processsignal transduction
A0009615biological_processresponse to virus
A0019904molecular_functionprotein domain specific binding
A0030136cellular_componentclathrin-coated vesicle
A0032991cellular_componentprotein-containing complex
A0036094molecular_functionsmall molecule binding
A0042562molecular_functionhormone binding
A0042572biological_processretinol metabolic process
A0046982molecular_functionprotein heterodimerization activity
A0051262biological_processprotein tetramerization
A0060417cellular_componentyolk
A0065003biological_processprotein-containing complex assembly
A0070324molecular_functionthyroid hormone binding
A0070327biological_processthyroid hormone transport
B0001555biological_processoocyte growth
B0005179molecular_functionhormone activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0006144biological_processpurine nucleobase metabolic process
B0007165biological_processsignal transduction
B0009615biological_processresponse to virus
B0019904molecular_functionprotein domain specific binding
B0030136cellular_componentclathrin-coated vesicle
B0032991cellular_componentprotein-containing complex
B0036094molecular_functionsmall molecule binding
B0042562molecular_functionhormone binding
B0042572biological_processretinol metabolic process
B0046982molecular_functionprotein heterodimerization activity
B0051262biological_processprotein tetramerization
B0060417cellular_componentyolk
B0065003biological_processprotein-containing complex assembly
B0070324molecular_functionthyroid hormone binding
B0070327biological_processthyroid hormone transport
Functional Information from PDB Data
site_idAC1
Number of Residues1
DetailsBINDING SITE FOR RESIDUE SO4 B 128
ChainResidue
BSER77

Functional Information from PROSITE/UniProt
site_idPS00768
Number of Residues16
DetailsTRANSTHYRETIN_1 Transthyretin signature 1. KVLDavrGsPAanVaV
ChainResidueDetails
ALYS15-VAL30

site_idPS00769
Number of Residues13
DetailsTRANSTHYRETIN_2 Transthyretin signature 2. YTIAalLSPFSYS
ChainResidueDetails
ATYR105-SER117

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:P02766
ChainResidueDetails
ALYS15
AGLU54
ASER117
BLYS15
BGLU54
BSER117

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Sulfocysteine => ECO:0000250|UniProtKB:P02766
ChainResidueDetails
ACYS10
BCYS10

222624

PDB entries from 2024-07-17

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