1TFB

NMR STUDIES OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB: DYNAMICS AND INTERACTION WITH VP16 ACTIVATION DOMAIN, 20 STRUCTURES

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006352	biological_process	DNA-templated transcription initiation
A	0017025	molecular_function	TBP-class protein binding
A	0070897	biological_process	transcription preinitiation complex assembly

Functional Information from PROSITE/UniProt

site_id	PS00782
Number of Residues	16
Details	TFIIB Transcription factor TFIIB repeat signature. GRandAIASACLYIAC

Chain	Residue	Details
A	GLY153-CYS168
A	GLY247-SER262

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	BINDING: BINDING => ECO:0000269|PubMed:27193682, ECO:0007744|PDB:5IYD

Chain	Residue	Details
A	LYS152
A	ARG290
A	ARG154
A	LYS189
A	LYS196
A	ARG248
A	LYS272
A	ALA281
A	THR284
A	ARG286

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; by autocatalysis => ECO:0000269|PubMed:12931194

Chain	Residue	Details
A	LYS238

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