1TEE

Crystal structure of C205F mutant of PKS18 from Mycobacterium tuberculosis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006633	biological_process	fatty acid biosynthetic process
A	0009058	biological_process	biosynthetic process
A	0009715	biological_process	chalcone biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006633	biological_process	fatty acid biosynthetic process
B	0009058	biological_process	biosynthetic process
B	0009715	biological_process	chalcone biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006633	biological_process	fatty acid biosynthetic process
C	0009058	biological_process	biosynthetic process
C	0009715	biological_process	chalcone biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0006629	biological_process	lipid metabolic process
D	0006631	biological_process	fatty acid metabolic process
D	0006633	biological_process	fatty acid biosynthetic process
D	0009058	biological_process	biosynthetic process
D	0009715	biological_process	chalcone biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"15286723","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15286723","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Site: {"description":"Important for broad specificity for aliphatic long-chain acyl-CoA starter units"}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
A	CYS175
A	PHE224
A	HIS313
A	ASN346

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
B	CYS175
B	PHE224
B	HIS313
B	ASN346

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
C	CYS175
C	PHE224
C	HIS313
C	ASN346

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1cgk

Chain	Residue	Details
D	CYS175
D	PHE224
D	HIS313
D	ASN346

---