1TD1
Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with acetate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0047975 | molecular_function | guanosine phosphorylase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0047975 | molecular_function | guanosine phosphorylase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0047975 | molecular_function | guanosine phosphorylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ACT A 700 |
| Chain | Residue |
| A | ALA119 |
| A | HOH757 |
| A | GLY120 |
| A | TYR202 |
| A | GLU203 |
| A | VAL219 |
| A | GLY220 |
| A | MET221 |
| A | ASN245 |
| A | HOH750 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE ACT B 701 |
| Chain | Residue |
| B | ALA118 |
| B | ALA119 |
| B | GLY120 |
| B | TYR202 |
| B | GLU203 |
| B | VAL219 |
| B | GLY220 |
| B | ASN245 |
| B | HOH745 |
| B | HOH780 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ACT C 702 |
| Chain | Residue |
| C | ALA119 |
| C | GLY120 |
| C | TYR202 |
| C | GLU203 |
| C | VAL219 |
| C | GLY220 |
| C | ASN245 |
| C | HOH758 |
| C | HOH786 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ula |
| Chain | Residue | Details |
| A | ASN245 | |
| A | HIS88 | |
| A | GLU91 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ula |
| Chain | Residue | Details |
| B | ASN245 | |
| B | HIS88 | |
| B | GLU91 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ula |
| Chain | Residue | Details |
| C | ASN245 | |
| C | HIS88 | |
| C | GLU91 |
