1TD1

Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with acetate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004731	molecular_function	purine-nucleoside phosphorylase activity
A	0005737	cellular_component	cytoplasm
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0009116	biological_process	nucleoside metabolic process
A	0016740	molecular_function	transferase activity
A	0016757	molecular_function	glycosyltransferase activity
A	0047975	molecular_function	guanosine phosphorylase activity
B	0003824	molecular_function	catalytic activity
B	0004731	molecular_function	purine-nucleoside phosphorylase activity
B	0005737	cellular_component	cytoplasm
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0009116	biological_process	nucleoside metabolic process
B	0016740	molecular_function	transferase activity
B	0016757	molecular_function	glycosyltransferase activity
B	0047975	molecular_function	guanosine phosphorylase activity
C	0003824	molecular_function	catalytic activity
C	0004731	molecular_function	purine-nucleoside phosphorylase activity
C	0005737	cellular_component	cytoplasm
C	0006139	biological_process	nucleobase-containing compound metabolic process
C	0009116	biological_process	nucleoside metabolic process
C	0016740	molecular_function	transferase activity
C	0016757	molecular_function	glycosyltransferase activity
C	0047975	molecular_function	guanosine phosphorylase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ACT A 700

Chain	Residue
A	ALA119
A	HOH757
A	GLY120
A	TYR202
A	GLU203
A	VAL219
A	GLY220
A	MET221
A	ASN245
A	HOH750

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site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE ACT B 701

Chain	Residue
B	ALA118
B	ALA119
B	GLY120
B	TYR202
B	GLU203
B	VAL219
B	GLY220
B	ASN245
B	HOH745
B	HOH780

---

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE ACT C 702

Chain	Residue
C	ALA119
C	GLY120
C	TYR202
C	GLU203
C	VAL219
C	GLY220
C	ASN245
C	HOH758
C	HOH786

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1ula

Chain	Residue	Details
A	ASN245
A	HIS88
A	GLU91

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1ula

Chain	Residue	Details
B	ASN245
B	HIS88
B	GLU91

---

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1ula

Chain	Residue	Details
C	ASN245
C	HIS88
C	GLU91

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