1TCV
Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with Non-detergent Sulfobetaine 195 and acetate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0009116 | biological_process | nucleoside metabolic process |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0047975 | molecular_function | guanosine phosphorylase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| B | 0009116 | biological_process | nucleoside metabolic process |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0047975 | molecular_function | guanosine phosphorylase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004731 | molecular_function | purine-nucleoside phosphorylase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| C | 0009116 | biological_process | nucleoside metabolic process |
| C | 0016757 | molecular_function | glycosyltransferase activity |
| C | 0047975 | molecular_function | guanosine phosphorylase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ACT A 900 |
| Chain | Residue |
| A | ALA119 |
| A | GLY120 |
| A | TYR202 |
| A | GLU203 |
| A | VAL219 |
| A | GLY220 |
| A | MET221 |
| A | ASN245 |
| A | NDS951 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT B 901 |
| Chain | Residue |
| B | ALA119 |
| B | GLY120 |
| B | TYR202 |
| B | GLU203 |
| B | VAL219 |
| B | GLY220 |
| B | ASN245 |
| B | NDS952 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT C 902 |
| Chain | Residue |
| C | ALA119 |
| C | GLY120 |
| C | TYR202 |
| C | GLU203 |
| C | VAL219 |
| C | ASN245 |
| C | NDS953 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE NDS A 951 |
| Chain | Residue |
| A | GLY34 |
| A | SER35 |
| A | ARG86 |
| A | HIS88 |
| A | ASN117 |
| A | ALA118 |
| A | TYR202 |
| A | SER222 |
| A | ACT900 |
| A | HOH1016 |
| B | PHE161 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE NDS B 952 |
| Chain | Residue |
| B | SER35 |
| B | ARG86 |
| B | HIS88 |
| B | TYR90 |
| B | ASN117 |
| B | ALA118 |
| B | TYR202 |
| B | MET221 |
| B | SER222 |
| B | VAL262 |
| B | ACT901 |
| B | HOH966 |
| C | PHE161 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE NDS C 953 |
| Chain | Residue |
| A | PHE161 |
| C | ARG86 |
| C | HIS88 |
| C | TYR90 |
| C | ALA118 |
| C | TYR202 |
| C | MET221 |
| C | SER222 |
| C | THR244 |
| C | VAL262 |
| C | ACT902 |
| C | HOH987 |
| C | HOH1031 |
| C | HOH1050 |
