1TCJ

STRUCTURE-ACTIVITY RELATIONSHIPS OF MU-CONOTOXIN GIIIA: STRUCTURE DETERMINATION OF ACTIVE AND INACTIVE SODIUM CHANNEL BLOCKER PEPTIDES BY NMR AND SIMULATED ANNEALING CALCULATIONS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0019871	molecular_function	sodium channel inhibitor activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NH2 A 23

Chain	Residue
A	CYS21
A	ALA22

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Functional Information from PROSITE/UniProt

site_id	PS60013
Number of Residues	19
Details	MU_CONOTOXIN Mu-conotoxin family signature. CCTPPkkCKDRQCKPQ.RCC

Chain	Residue	Details
A	CYS3-CYS21

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