Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003911 | molecular_function | DNA ligase (NAD+) activity |
| B | 0003911 | molecular_function | DNA ligase (NAD+) activity |
| C | 0003911 | molecular_function | DNA ligase (NAD+) activity |
| D | 0003911 | molecular_function | DNA ligase (NAD+) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 405 |
| Chain | Residue |
| A | TYR30 |
| A | LEU124 |
| A | ALA125 |
| A | ARG141 |
| A | ARG202 |
| A | HOH416 |
| A | HOH453 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 406 |
| Chain | Residue |
| A | ARG129 |
| A | ARG137 |
| A | LYS79 |
| A | PRO81 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 407 |
| Chain | Residue |
| A | ARG190 |
| A | PHE198 |
| A | ARG220 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 408 |
| Chain | Residue |
| A | PRO81 |
| A | HIS82 |
| A | ASP83 |
| A | SER127 |
| A | ARG129 |
| A | ARG137 |
| A | GLU171 |
| A | ARG173 |
| A | HOH415 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 409 |
| Chain | Residue |
| A | SER26 |
| A | TYR30 |
| A | TYR42 |
| A | ARG68 |
| A | LYS306 |
| A | NAD401 |
| A | HOH413 |
| A | HOH422 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 410 |
| Chain | Residue |
| C | THR304 |
| C | ARG309 |
| C | HOH445 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 411 |
| Chain | Residue |
| A | ARG14 |
| B | TRP268 |
| B | HIS275 |
| B | TYR314 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 412 |
| Chain | Residue |
| B | TYR30 |
| B | LEU124 |
| B | ALA125 |
| B | ARG141 |
| B | ARG202 |
| B | HOH537 |
| B | HOH566 |
| B | HOH575 |
| B | HOH581 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 413 |
| Chain | Residue |
| B | ARG129 |
| B | ARG137 |
| B | HOH561 |
| B | HOH577 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 415 |
| Chain | Residue |
| B | HIS82 |
| B | ASP83 |
| B | SER127 |
| B | ARG129 |
| B | ARG137 |
| B | GLU171 |
| B | ARG173 |
| B | HOH555 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 417 |
| Chain | Residue |
| A | HOH426 |
| B | TYR177 |
| B | PRO179 |
| B | ASN223 |
| B | ARG253 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 418 |
| Chain | Residue |
| B | THR304 |
| B | ARG309 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 419 |
| Chain | Residue |
| A | TRP268 |
| A | GLU272 |
| A | HIS275 |
| A | TYR314 |
| B | ARG14 |
| B | GLN21 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 420 |
| Chain | Residue |
| B | VAL160 |
| B | PRO161 |
| B | MET162 |
| B | ARG163 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 421 |
| Chain | Residue |
| C | TYR30 |
| C | LEU124 |
| C | ALA125 |
| C | ARG141 |
| C | ARG202 |
| C | HOH434 |
| C | HOH457 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 422 |
| Chain | Residue |
| C | PRO81 |
| C | ARG129 |
| C | ARG137 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 423 |
| Chain | Residue |
| C | HIS82 |
| C | ASP83 |
| C | SER127 |
| C | ARG129 |
| C | ARG137 |
| C | GLU171 |
| C | ARG173 |
| C | HOH430 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 424 |
| Chain | Residue |
| C | TRP268 |
| C | GLU272 |
| C | HIS275 |
| C | TYR314 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 425 |
| Chain | Residue |
| D | LEU124 |
| D | ALA125 |
| D | ARG141 |
| D | ARG202 |
| D | HOH537 |
| D | HOH570 |
| D | TYR30 |
| site_id | CC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 426 |
| Chain | Residue |
| D | ARG129 |
| D | ARG137 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 427 |
| Chain | Residue |
| D | ARG190 |
| D | ARG220 |
| site_id | CC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 D 428 |
| Chain | Residue |
| D | PRO81 |
| D | HIS82 |
| D | ASP83 |
| D | SER127 |
| D | ARG129 |
| D | ARG137 |
| D | GLU171 |
| D | ARG173 |
| D | HOH556 |
| site_id | CC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 429 |
| Chain | Residue |
| D | THR304 |
| D | ARG309 |
| site_id | CC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 430 |
| Chain | Residue |
| D | HIS275 |
| D | TYR314 |
| D | HOH552 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NA B 531 |
| Chain | Residue |
| B | GLU38 |
| B | ASP39 |
| B | ASN200 |
| site_id | CC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAD A 401 |
| Chain | Residue |
| A | TYR25 |
| A | TYR29 |
| A | TYR30 |
| A | VAL37 |
| A | GLU38 |
| A | ASP39 |
| A | TYR42 |
| A | ASP43 |
| A | SER88 |
| A | LEU89 |
| A | ASP91 |
| A | GLU118 |
| A | LEU119 |
| A | LYS120 |
| A | ILE121 |
| A | ALA125 |
| A | ARG141 |
| A | GLU175 |
| A | TYR227 |
| A | VAL289 |
| A | LYS291 |
| A | LYS315 |
| A | SO4409 |
| A | HOH413 |
| A | HOH416 |
| site_id | CC9 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NAD B 402 |
| Chain | Residue |
| B | TYR25 |
| B | SER26 |
| B | TYR29 |
| B | TYR30 |
| B | VAL37 |
| B | ASP39 |
| B | TYR42 |
| B | ASP43 |
| B | TYR87 |
| B | SER88 |
| B | LEU89 |
| B | ASP91 |
| B | GLU118 |
| B | LEU119 |
| B | LYS120 |
| B | ILE121 |
| B | ALA125 |
| B | ARG141 |
| B | GLU175 |
| B | TYR227 |
| B | VAL289 |
| B | LYS291 |
| B | LYS315 |
| B | HOH537 |
| B | HOH543 |
| site_id | DC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAD C 403 |
| Chain | Residue |
| C | SER26 |
| C | TYR29 |
| C | TYR30 |
| C | VAL37 |
| C | GLU38 |
| C | ASP39 |
| C | TYR42 |
| C | ASP43 |
| C | SER88 |
| C | LEU89 |
| C | ASP91 |
| C | GLU118 |
| C | LEU119 |
| C | LYS120 |
| C | ILE121 |
| C | ALA125 |
| C | ARG141 |
| C | GLU175 |
| C | TYR227 |
| C | VAL289 |
| C | LYS291 |
| C | LYS315 |
| C | HOH425 |
| C | HOH457 |
| site_id | DC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAD D 404 |
| Chain | Residue |
| D | TYR25 |
| D | TYR29 |
| D | TYR30 |
| D | VAL37 |
| D | ASP39 |
| D | TYR42 |
| D | ASP43 |
| D | TYR87 |
| D | SER88 |
| D | LEU89 |
| D | ASP91 |
| D | GLU118 |
| D | LEU119 |
| D | LYS120 |
| D | ILE121 |
| D | ALA125 |
| D | ARG141 |
| D | GLU175 |
| D | TYR227 |
| D | LYS291 |
| D | LYS315 |
| D | HOH534 |
| D | HOH537 |
| D | HOH545 |
Functional Information from PROSITE/UniProt
| site_id | PS01055 |
| Number of Residues | 30 |
| Details | DNA_LIGASE_N1 NAD-dependent DNA ligase signature 1. KIDGLAislrYenGvFvrgaTRGDGtvGEN |
| Chain | Residue | Details |
| A | LYS120-ASN149 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LYS120 | |
| B | LYS120 | |
| C | LYS120 | |
| D | LYS120 | |
| Chain | Residue | Details |
| A | GLU175 | |
| A | LYS291 | |
| A | LYS315 | |
| B | ASP39 | |
| B | SER88 | |
| B | GLU118 | |
| B | ARG141 | |
| B | GLU175 | |
| B | LYS291 | |
| B | LYS315 | |
| C | ASP39 | |
| C | SER88 | |
| C | GLU118 | |
| C | ARG141 | |
| C | GLU175 | |
| C | LYS291 | |
| C | LYS315 | |
| D | ASP39 | |
| D | SER88 | |
| D | GLU118 | |
| D | ARG141 | |
| D | GLU175 | |
| D | LYS291 | |
| D | LYS315 | |
| A | ASP39 | |
| A | SER88 | |
| A | GLU118 | |
| A | ARG141 | |
