1T9K
X-ray crystal structure of aIF-2B alpha subunit-related translation initiation factor [Thermotoga maritima]
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009086 | biological_process | methionine biosynthetic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| A | 0046523 | molecular_function | S-methyl-5-thioribose-1-phosphate isomerase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009086 | biological_process | methionine biosynthetic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| B | 0046523 | molecular_function | S-methyl-5-thioribose-1-phosphate isomerase activity |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009086 | biological_process | methionine biosynthetic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| C | 0046523 | molecular_function | S-methyl-5-thioribose-1-phosphate isomerase activity |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009086 | biological_process | methionine biosynthetic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0019509 | biological_process | L-methionine salvage from methylthioadenosine |
| D | 0046523 | molecular_function | S-methyl-5-thioribose-1-phosphate isomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 401 |
| Chain | Residue |
| A | ARG48 |
| A | GLY49 |
| A | ARG88 |
| A | CYS154 |
| A | GLN193 |
| A | LYS245 |
| A | HOH445 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 403 |
| Chain | Residue |
| C | ARG88 |
| C | GLN193 |
| C | LYS245 |
| C | HOH436 |
| C | ARG48 |
| C | GLY49 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 406 |
| Chain | Residue |
| A | LYS256 |
| B | ARG257 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 411 |
| Chain | Residue |
| B | ARG48 |
| B | GLY49 |
| B | ARG88 |
| B | CYS154 |
| B | GLN193 |
| B | LYS245 |
| B | HOH442 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 413 |
| Chain | Residue |
| D | ARG48 |
| D | GLY49 |
| D | ARG88 |
| D | GLN193 |
| D | LYS245 |
| D | HOH446 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 416 |
| Chain | Residue |
| A | ARG257 |
| B | LYS256 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_01678","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01678","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_01678","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
