1T97
Use of sequence duplication to engineer a ligand-triggered long-distance molecular switch in T4 Lysozyme
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003796 | molecular_function | lysozyme activity |
A | 0009253 | biological_process | peptidoglycan catabolic process |
A | 0016998 | biological_process | cell wall macromolecule catabolic process |
B | 0003796 | molecular_function | lysozyme activity |
B | 0009253 | biological_process | peptidoglycan catabolic process |
B | 0016998 | biological_process | cell wall macromolecule catabolic process |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098 |
Chain | Residue | Details |
A | GLU11 | |
B | GLU11 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04110, ECO:0000269|PubMed:1892846, ECO:0000269|PubMed:3382407, ECO:0000269|PubMed:7831309, ECO:0000269|PubMed:8266098 |
Chain | Residue | Details |
A | ASP20 | |
B | ASP20 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:8266098 |
Chain | Residue | Details |
A | LEU32 | |
A | PHE115 | |
B | LEU32 | |
B | PHE115 |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000303|PubMed:7831309 |
Chain | Residue | Details |
A | SER128 | |
A | ASN143 | |
B | SER128 | |
B | ASN143 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 206l |
Chain | Residue | Details |
A | GLU11 | |
A | ASP20 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 206l |
Chain | Residue | Details |
B | GLU11 | |
B | ASP20 |
site_id | MCSA1 |
Number of Residues | 2 |
Details | M-CSA 921 |
Chain | Residue | Details |
A | GLU11 | proton shuttle (general acid/base) |
A | ASP20 | covalent catalysis |
site_id | MCSA2 |
Number of Residues | 2 |
Details | M-CSA 921 |
Chain | Residue | Details |
B | GLU11 | proton shuttle (general acid/base) |
B | ASP20 | covalent catalysis |