1T6C

Structural characterization of the Ppx/GppA protein family: crystal structure of the Aquifex aeolicus family member

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0008894	molecular_function	guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity
A	0015949	biological_process	nucleobase-containing small molecule interconversion
A	0016462	molecular_function	pyrophosphatase activity
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 501

Chain	Residue
A	TYR226

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 502

Chain	Residue
A	ASP141
A	GLY143
A	SER146
A	GLU148
A	HOH685
A	HOH689

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 503

Chain	Residue
A	GLY145
A	GLY166
A	ILE167
A	GLN142
A	GLY143

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 504

Chain	Residue
A	GLY166
A	ASN169
A	HOH624
A	HOH972

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 505

Chain	Residue
A	GLN142
A	ARG267

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MPD A 600

Chain	Residue
A	LYS78
A	LYS258
A	HOH803
A	HOH975

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MPD A 601

Chain	Residue
A	HIS232
A	HOH976

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site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MPD A 602

Chain	Residue
A	GLU80
A	ARG81
A	VAL82
A	ARG259
A	MPD603
A	HOH695

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site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MPD A 603

Chain	Residue
A	ARG81
A	TRP244
A	THR247
A	GLU309
A	MPD602
A	HOH966

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site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MPD A 604

Chain	Residue
A	GLU136
A	LYS153
A	ARG158
A	TYR238
A	GLU283
A	HOH649
A	HOH753
A	HOH759

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site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MPD A 605

Chain	Residue
A	GLN118
A	TYR122
A	LEU125
A	SER304

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