1T2Q

The Crystal Structure of an NNA7 Fab that recognizes an N-type blood group antigen

Functional Information from GO Data

Chain	GOid	namespace	contents
H	0002250	biological_process	adaptive immune response
H	0002376	biological_process	immune system process
H	0003823	molecular_function	antigen binding
H	0005576	cellular_component	extracellular region
H	0016064	biological_process	immunoglobulin mediated immune response
H	0019814	cellular_component	immunoglobulin complex
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0019814	cellular_component	immunoglobulin complex
L	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MES H 801

Chain	Residue
H	GLY34
H	TRP53
H	SER54
H	ASN99
H	TYR104
H	PRO206
H	THR210
H	LYS211

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL L 701

Chain	Residue
L	ARG161
L	ARG194
L	HIS195
L	HOH818
L	HOH839
L	HOH847
L	LYS113

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL H 702

Chain	Residue
H	TYR104
H	PRO206
H	SER209
H	HOH820
H	HOH844
H	HOH911
L	HIS32
L	GLY97

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR198-HIS204

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