1T1I

High Resolution Crystal Structure of Mutant W129A of Kumamolisin, a Sedolisin Type Proteinase (previously called Kumamolysin or KSCP)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004252	molecular_function	serine-type endopeptidase activity
A	0006508	biological_process	proteolysis
A	0008236	molecular_function	serine-type peptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 365

Chain	Residue
A	ASP316
A	ILE317
A	GLY334
A	GLY336
A	ASP338
A	HOH368

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site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE SO4 A 366

Chain	Residue
A	TYR186
A	SER198
A	ALA199
A	PHE225
A	PRO226
A	HOH384
A	HOH404
A	HOH407
A	HOH412
A	HOH431
A	HOH433
A	HOH475
A	HOH491
A	HOH562
A	HOH667
A	ASN145
A	ARG146
A	LEU149

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site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 367

Chain	Residue
A	LYS121
A	ARG327
A	ARG329
A	HOH387
A	HOH415
A	HOH466
A	HOH524
A	HOH597

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