1T0Z
Structure of an Excitatory Insect-specific Toxin with an Analgesic Effect on Mammalian from Scorpion Buthus martensii Karsch
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006952 | biological_process | defense response |
| A | 0008200 | molecular_function | ion channel inhibitor activity |
| A | 0017080 | molecular_function | sodium channel regulator activity |
| A | 0019871 | molecular_function | sodium channel inhibitor activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006952 | biological_process | defense response |
| B | 0008200 | molecular_function | ion channel inhibitor activity |
| B | 0017080 | molecular_function | sodium channel regulator activity |
| B | 0019871 | molecular_function | sodium channel inhibitor activity |
| B | 0035821 | biological_process | modulation of process of another organism |
| B | 0090729 | molecular_function | toxin activity |
| B | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 101 |
| Chain | Residue |
| A | CYS16 |
| A | LEU17 |
| A | PHE18 |
| A | TYR21 |
| A | LEU71 |
| A | HOH149 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 102 |
| Chain | Residue |
| A | TYR63 |
| A | SO4103 |
| A | CYS37 |
| A | CYS38 |
| A | LEU39 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 103 |
| Chain | Residue |
| A | TYR36 |
| A | TYR63 |
| A | VAL66 |
| A | SO4102 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 104 |
| Chain | Residue |
| A | ASP65 |
| A | GLN67 |
| A | SO4110 |
| A | HOH151 |
| B | LEU71 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 105 |
| Chain | Residue |
| A | TRP57 |
| A | SO4108 |
| A | HOH147 |
| B | GLU15 |
| B | TYR21 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 106 |
| Chain | Residue |
| B | CYS37 |
| B | CYS38 |
| B | LEU39 |
| B | TYR63 |
| B | HOH122 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 107 |
| Chain | Residue |
| A | ILE56 |
| A | TRP57 |
| A | THR60 |
| A | HOH114 |
| B | SER9 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 108 |
| Chain | Residue |
| A | ASP58 |
| A | SER59 |
| A | SO4105 |
| B | CYS16 |
| B | LEU17 |
| B | PHE18 |
| B | TYR21 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 109 |
| Chain | Residue |
| B | TRP57 |
| B | ASP58 |
| B | SER59 |
| B | HOH115 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 110 |
| Chain | Residue |
| A | LYS34 |
| A | ILE68 |
| A | ILE69 |
| A | SO4104 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 111 |
| Chain | Residue |
| B | ASP55 |
| B | ILE56 |
| B | TRP57 |
| B | THR60 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 126 |
| Details | Domain: {"description":"LCN-type CS-alpha/beta","evidences":[{"source":"PROSITE-ProRule","id":"PRU01210","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
