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1SZV

Structure of the Adaptor Protein p14 reveals a Profilin-like Fold with Novel Function

Functional Information from GO Data
ChainGOidnamespacecontents
A0001558biological_processregulation of cell growth
A0005085molecular_functionguanyl-nucleotide exchange factor activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005765cellular_componentlysosomal membrane
A0005770cellular_componentlate endosome
A0008104biological_processintracellular protein localization
A0010761biological_processfibroblast migration
A0031902cellular_componentlate endosome membrane
A0032008biological_processpositive regulation of TOR signaling
A0038202biological_processTORC1 signaling
A0043410biological_processpositive regulation of MAPK cascade
A0060090molecular_functionmolecular adaptor activity
A0071230biological_processcellular response to amino acid stimulus
A0071986cellular_componentRagulator complex
A0150116biological_processregulation of cell-substrate junction organization
A1902414biological_processprotein localization to cell junction
A1902533biological_processpositive regulation of intracellular signal transduction
A1904263biological_processpositive regulation of TORC1 signaling
A1990877cellular_componentFNIP-folliculin RagC/D GAP
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues13
DetailsRegion: {"description":"Required for location at endosomes"}
ChainResidueDetails

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PDB entries from 2026-03-11

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