Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE FMN A 5570 |
| Chain | Residue |
| A | TYR143 |
| A | THR280 |
| A | LYS349 |
| A | SER371 |
| A | HIS373 |
| A | GLY374 |
| A | ARG376 |
| A | ASP409 |
| A | GLY410 |
| A | GLY411 |
| A | ARG413 |
| A | TYR144 |
| A | GLY432 |
| A | ARG433 |
| A | 1735580 |
| A | HOH5600 |
| A | HOH5616 |
| A | SER195 |
| A | ALA196 |
| A | THR197 |
| A | ALA198 |
| A | SER228 |
| A | GLN252 |
| A | TYR254 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE FMN B 9570 |
| Chain | Residue |
| B | TYR143 |
| B | TYR144 |
| B | SER195 |
| B | ALA196 |
| B | THR197 |
| B | ALA198 |
| B | SER228 |
| B | GLN252 |
| B | TYR254 |
| B | THR280 |
| B | LYS349 |
| B | SER371 |
| B | HIS373 |
| B | GLY374 |
| B | ARG376 |
| B | ASP409 |
| B | GLY410 |
| B | GLY411 |
| B | ARG413 |
| B | LEU431 |
| B | GLY432 |
| B | ARG433 |
| B | 1739580 |
| B | HOH9582 |
| B | HOH9598 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 173 A 5580 |
| Chain | Residue |
| A | TYR143 |
| A | TYR254 |
| A | ILE326 |
| A | HIS373 |
| A | ARG376 |
| A | FMN5570 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 173 B 9580 |
| Chain | Residue |
| B | TYR143 |
| B | ALA230 |
| B | TYR254 |
| B | HIS373 |
| B | ARG376 |
| B | FMN9570 |
Functional Information from PROSITE/UniProt
| site_id | PS00191 |
| Number of Residues | 8 |
| Details | CYTOCHROME_B5_1 Cytochrome b5 family, heme-binding domain signature. FLPNHPGG |
| Chain | Residue | Details |
| A | PHE39-GLY46 | |
| site_id | PS00557 |
| Number of Residues | 7 |
| Details | FMN_HYDROXY_ACID_DH_1 FMN-dependent alpha-hydroxy acid dehydrogenases active site. SNHGGRQ |
| Chain | Residue | Details |
| A | SER371-GLN377 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | HIS373 | |
| B | HIS373 | |
| Chain | Residue | Details |
| A | HIS43 | |
| A | HIS66 | |
| B | HIS43 | |
| B | HIS66 | |
| Chain | Residue | Details |
| A | TYR97 | |
| A | ARG376 | |
| A | ASP409 | |
| A | GLY432 | |
| B | TYR97 | |
| B | TYR143 | |
| B | SER195 | |
| B | SER228 | |
| B | GLN252 | |
| B | TYR254 | |
| B | THR280 | |
| A | TYR143 | |
| B | LYS349 | |
| B | HIS373 | |
| B | ARG376 | |
| B | ASP409 | |
| B | GLY432 | |
| A | SER195 | |
| A | SER228 | |
| A | GLN252 | |
| A | TYR254 | |
| A | THR280 | |
| A | LYS349 | |
| A | HIS373 | |
| Chain | Residue | Details |
| A | GLN139 | |
| A | LYS296 | |
| B | GLN139 | |
| B | LYS296 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 102 |
| Chain | Residue | Details |
| A | TYR254 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP282 | electrostatic stabiliser, hydrogen bond acceptor |
| A | HIS373 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 102 |
| Chain | Residue | Details |
| B | TYR254 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP282 | electrostatic stabiliser, hydrogen bond acceptor |
| B | HIS373 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
