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1SXR

Drosophila Peptidoglycan Recognition Protein (PGRP)-SA

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0006508biological_processproteolysis
A0006965biological_processpositive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
A0008233molecular_functionpeptidase activity
A0008270molecular_functionzinc ion binding
A0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
A0009253biological_processpeptidoglycan catabolic process
A0016019molecular_functionpeptidoglycan immune receptor activity
A0032494biological_processresponse to peptidoglycan
A0032500molecular_functionmuramyl dipeptide binding
A0038187molecular_functionpattern recognition receptor activity
A0042834molecular_functionpeptidoglycan binding
A0045087biological_processinnate immune response
A0050830biological_processdefense response to Gram-positive bacterium
A0106415molecular_functionmuramoyltetrapeptide carboxypeptidase activity
A0160032biological_processToll receptor ligand protein activation cascade
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0006508biological_processproteolysis
B0006965biological_processpositive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria
B0008233molecular_functionpeptidase activity
B0008270molecular_functionzinc ion binding
B0008745molecular_functionN-acetylmuramoyl-L-alanine amidase activity
B0009253biological_processpeptidoglycan catabolic process
B0016019molecular_functionpeptidoglycan immune receptor activity
B0032494biological_processresponse to peptidoglycan
B0032500molecular_functionmuramyl dipeptide binding
B0038187molecular_functionpattern recognition receptor activity
B0042834molecular_functionpeptidoglycan binding
B0045087biological_processinnate immune response
B0050830biological_processdefense response to Gram-positive bacterium
B0106415molecular_functionmuramoyltetrapeptide carboxypeptidase activity
B0160032biological_processToll receptor ligand protein activation cascade
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE SO4 A 401
ChainResidue
AGLY101
ATYR102
AASN103
AALA104
AHOH422
AHOH425
AHOH545
BHIS29
BARG95

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE SO4 B 402
ChainResidue
AHIS29
AARG95
BGLY101
BTYR102
BASN103
BALA104
BHOH417
BHOH432
BHOH503

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO B 403
ChainResidue
BHIS65
BLEU69
BSER75
BTYR76
BHOH423
BHOH448

site_idAC4
Number of Residues7
DetailsBINDING SITE FOR RESIDUE EDO A 404
ChainResidue
AHIS65
ALEU69
ASER75
ATYR76
AHOH437
AHOH442
AHOH561

site_idAC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO A 405
ChainResidue
AVAL32
AARG33

site_idAC6
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO A 406
ChainResidue
AHIS180
AHIS181

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Interacts with peptidoglycan => ECO:0000305
ChainResidueDetails
ATHR156
BTHR156

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PDB entries from 2024-07-24

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