1SRA

STRUCTURE OF A NOVEL EXTRACELLULAR CA2+-BINDING MODULE IN BM-40(SLASH)SPARC(SLASH)OSTEONECTIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0005615	cellular_component	extracellular space

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 301

Chain	Residue
A	ASP222
A	PRO225
A	ASP227
A	TYR229
A	GLU234
A	HOH408

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 302

Chain	Residue
A	ASP257
A	ASP259
A	ASP261
A	TYR263
A	GLU268
A	HOH405

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 303

Chain	Residue
A	PRO241
A	ILE243
A	GLU246
A	HOH416
A	HOH488

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site_id	EF1
Number of Residues	5
Details	EF-HAND 1 TO WHICH CA+2(301) IS BOUND; CA+2 LIGANDS ARE LISTED

Chain	Residue
A	ASP222
A	PRO225
A	ASP227
A	TYR229
A	GLU234

---

site_id	EF2
Number of Residues	5
Details	EF-HAND 2 TO WHICH CA+2(302) IS BOUND

Chain	Residue
A	GLU268
A	ASP257
A	ASP259
A	ASP261
A	TYR263

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site_id	MET
Number of Residues	3
Details	BINDING SITE FOR THIRD, UNIDENTIFIED METAL ION MODELED AS CALCIUM CA+2(303)

Chain	Residue
A	ALA240
A	LEU242
A	MET245

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DLDNDKYIAldEW

Chain	Residue	Details
A	ASP257-TRP269

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site_id	PS00613
Number of Residues	11
Details	OSTEONECTIN_2 Osteonectin domain signature 2. FPlRMrDWLkN

Chain	Residue	Details
A	PHE146-ASN156

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Domain: {"description":"EF-hand"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10142","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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