1SQ9

Structure of Ski8p, a WD repeat protein involved in mRNA degradation and meiotic recombination

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000228	cellular_component	nuclear chromosome
A	0003674	molecular_function	molecular_function
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005694	cellular_component	chromosome
A	0005737	cellular_component	cytoplasm
A	0006402	biological_process	mRNA catabolic process
A	0007131	biological_process	reciprocal meiotic recombination
A	0016593	cellular_component	Cdc73/Paf1 complex
A	0034427	biological_process	obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
A	0051321	biological_process	meiotic cell cycle
A	0051607	biological_process	defense response to virus
A	0055087	cellular_component	Ski complex
A	0065003	biological_process	protein-containing complex assembly
A	0065004	biological_process	protein-DNA complex assembly
A	0070478	biological_process	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay
A	0070481	biological_process	nuclear-transcribed mRNA catabolic process, non-stop decay

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 A 400

Chain	Residue
A	LYS128
A	LYS240
A	SER298
A	LYS361
A	HOH432
A	HOH433
A	HOH485
A	HOH530
A	HOH536

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 401

Chain	Residue
A	VAL276
A	ARG316
A	ARG325
A	THR328

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Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. TVSCsgDgYLKVWDN

Chain	Residue	Details
A	THR29-ASN43
A	LEU306-VAL320

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