1SQ9
Structure of Ski8p, a WD repeat protein involved in mRNA degradation and meiotic recombination
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000228 | cellular_component | nuclear chromosome |
| A | 0000956 | biological_process | nuclear-transcribed mRNA catabolic process |
| A | 0003674 | molecular_function | molecular_function |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005694 | cellular_component | chromosome |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006402 | biological_process | mRNA catabolic process |
| A | 0007131 | biological_process | reciprocal meiotic recombination |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0051321 | biological_process | meiotic cell cycle |
| A | 0051607 | biological_process | defense response to virus |
| A | 0055087 | cellular_component | Ski complex |
| A | 0065003 | biological_process | protein-containing complex assembly |
| A | 0065004 | biological_process | protein-DNA complex assembly |
| A | 0070478 | biological_process | nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay |
| A | 0070481 | biological_process | nuclear-transcribed mRNA catabolic process, non-stop decay |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 400 |
| Chain | Residue |
| A | LYS128 |
| A | LYS240 |
| A | SER298 |
| A | LYS361 |
| A | HOH432 |
| A | HOH433 |
| A | HOH485 |
| A | HOH530 |
| A | HOH536 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 401 |
| Chain | Residue |
| A | VAL276 |
| A | ARG316 |
| A | ARG325 |
| A | THR328 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. TVSCsgDgYLKVWDN |
| Chain | Residue | Details |
| A | THR29-ASN43 | |
| A | LEU306-VAL320 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 21 |
| Details | Repeat: {"description":"WD 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 34 |
| Details | Repeat: {"description":"WD 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 22 |
| Details | Repeat: {"description":"WD 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 26 |
| Details | Repeat: {"description":"WD 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 23 |
| Details | Repeat: {"description":"WD 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"WD 7"} |
| Chain | Residue | Details |
