1SO7

Maltose-induced structure of the human cytolsolic sialidase Neu2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004308	molecular_function	exo-alpha-sialidase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005764	cellular_component	lysosome
A	0005829	cellular_component	cytosol
A	0006516	biological_process	glycoprotein catabolic process
A	0006629	biological_process	lipid metabolic process
A	0006689	biological_process	ganglioside catabolic process
A	0009313	biological_process	oligosaccharide catabolic process
A	0016020	cellular_component	membrane
A	0016042	biological_process	lipid catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0046479	biological_process	glycosphingolipid catabolic process
A	1902494	cellular_component	catalytic complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 381

Chain	Residue
A	LEU28
A	GLY30
A	GLN31

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	11
Details	Repeat: {"description":"BNR 1"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	11
Details	Repeat: {"description":"BNR 2"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	3
Details	Motif: {"description":"FRIP motif"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Active site: {"description":"Nucleophile"}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Active site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	7
Details	Binding site: {}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1euu

Chain	Residue	Details
A	TYR334
A	GLU218

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