1SLC

X-RAY CRYSTALLOGRAPHY REVEALS CROSSLINKING OF MAMMALIAN LECTIN (GALECTIN-1) BY BIANTENNARY COMPLEX TYPE SACCHARIDES

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0006915	biological_process	apoptotic process
A	0016936	molecular_function	galactoside binding
A	0030246	molecular_function	carbohydrate binding
A	0030395	molecular_function	lactose binding
A	0043236	molecular_function	laminin binding
A	0062023	cellular_component	collagen-containing extracellular matrix
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005737	cellular_component	cytoplasm
B	0006915	biological_process	apoptotic process
B	0016936	molecular_function	galactoside binding
B	0030246	molecular_function	carbohydrate binding
B	0030395	molecular_function	lactose binding
B	0043236	molecular_function	laminin binding
B	0062023	cellular_component	collagen-containing extracellular matrix
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005737	cellular_component	cytoplasm
C	0006915	biological_process	apoptotic process
C	0016936	molecular_function	galactoside binding
C	0030246	molecular_function	carbohydrate binding
C	0030395	molecular_function	lactose binding
C	0043236	molecular_function	laminin binding
C	0062023	cellular_component	collagen-containing extracellular matrix
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005737	cellular_component	cytoplasm
D	0006915	biological_process	apoptotic process
D	0016936	molecular_function	galactoside binding
D	0030246	molecular_function	carbohydrate binding
D	0030395	molecular_function	lactose binding
D	0043236	molecular_function	laminin binding
D	0062023	cellular_component	collagen-containing extracellular matrix

Functional Information from PDB Data

site_id	G1C
Number of Residues	6
Details

Chain	Residue
A	ARG48
A	GLU71
A	ARG73
C	ARG48
C	GLU71
C	ARG73

---

site_id	GA1
Number of Residues	12
Details

Chain	Residue
A	HIS44
C	TRP68
C	ASN61
C	GLU71
A	ASN46
A	ARG48
A	TRP68
A	ASN61
A	GLU71
C	HIS44
C	ASN46
C	ARG48

---

site_id	GA2
Number of Residues	12
Details

Chain	Residue
B	HIS44
B	ASN46
B	ARG48
B	TRP68
B	ASN61
B	GLU71
D	HIS44
D	ASN46
D	ARG48
D	TRP68
D	ASN61
D	GLU71

---

site_id	GC2
Number of Residues	6
Details

Chain	Residue
B	ARG48
B	GLU71
B	ARG73
D	ARG48
D	GLU71
D	ARG73

---

site_id	MN1
Number of Residues	2
Details

Chain	Residue
A	GLY53
C	GLY53

---

site_id	MN2
Number of Residues	2
Details

Chain	Residue
B	GLY53
D	GLY53

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	PHE45
C	GLY53
C	SER62
C	GLY69
D	PHE45
D	GLY53
D	SER62
D	GLY69
A	GLY53
A	SER62
A	GLY69
B	PHE45
B	GLY53
B	SER62
B	GLY69
C	PHE45

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:P09382

Chain	Residue	Details
A	CYS2
B	CYS2
C	CYS2
D	CYS2

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P16045

Chain	Residue	Details
A	PRO13
A	ILE128
B	PRO13
B	ILE128
C	PRO13
C	ILE128
D	PRO13
D	ILE128

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P09382

Chain	Residue	Details
A	SER29
B	SER29
C	SER29
D	SER29

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P09382

Chain	Residue	Details
A	PHE30
B	PHE30
C	PHE30
D	PHE30

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:P16045

Chain	Residue	Details
A	PHE108
B	PHE108
C	PHE108
D	PHE108

---