1SFJ
2.4A Crystal structure of Staphylococcus aureus type I 3-dehydroquinase, with 3-dehydroquinate bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046279 | biological_process | 3,4-dihydroxybenzoate biosynthetic process |
| B | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046279 | biological_process | 3,4-dihydroxybenzoate biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE DHK A 239 |
| Chain | Residue |
| A | THR9 |
| A | GLN225 |
| A | GLU35 |
| A | ARG37 |
| A | ARG70 |
| A | HIS133 |
| A | LYS160 |
| A | ARG202 |
| A | TYR214 |
| A | ALA222 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE DHK B 239 |
| Chain | Residue |
| B | THR9 |
| B | GLU35 |
| B | ARG37 |
| B | ARG70 |
| B | HIS133 |
| B | LYS160 |
| B | ARG202 |
| B | TYR214 |
| B | ALA222 |
| B | GLN225 |
| B | HOH342 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_00214, ECO:0000269|PubMed:15229896 |
| Chain | Residue | Details |
| A | HIS133 | |
| B | HIS133 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Schiff-base intermediate with substrate => ECO:0000255|HAMAP-Rule:MF_00214, ECO:0000269|PubMed:15229896 |
| Chain | Residue | Details |
| A | LYS160 | |
| B | LYS160 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00214 |
| Chain | Residue | Details |
| A | GLU35 | |
| B | GLU35 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00214, ECO:0000269|PubMed:15229896 |
| Chain | Residue | Details |
| A | ARG70 | |
| A | ARG202 | |
| A | GLN225 | |
| B | ARG70 | |
| B | ARG202 | |
| B | GLN225 |
