1SAW
X-ray structure of homo sapiens protein FLJ36880
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0005829 | cellular_component | cytosol |
| A | 0006090 | biological_process | pyruvate metabolic process |
| A | 0006107 | biological_process | oxaloacetate metabolic process |
| A | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0018773 | molecular_function | acetylpyruvate hydrolase activity |
| A | 0034545 | molecular_function | fumarylpyruvate hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047621 | molecular_function | acylpyruvate hydrolase activity |
| A | 0050163 | molecular_function | oxaloacetate tautomerase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005759 | cellular_component | mitochondrial matrix |
| B | 0005829 | cellular_component | cytosol |
| B | 0006090 | biological_process | pyruvate metabolic process |
| B | 0006107 | biological_process | oxaloacetate metabolic process |
| B | 0008948 | molecular_function | oxaloacetate decarboxylase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0018773 | molecular_function | acetylpyruvate hydrolase activity |
| B | 0034545 | molecular_function | fumarylpyruvate hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047621 | molecular_function | acylpyruvate hydrolase activity |
| B | 0050163 | molecular_function | oxaloacetate tautomerase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG A 225 |
| Chain | Residue |
| A | GLU71 |
| A | GLU73 |
| A | ASP102 |
| A | LYS123 |
| A | HOH320 |
| A | HOH353 |
| A | HOH358 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MG B 225 |
| Chain | Residue |
| B | GLU73 |
| B | ASP102 |
| B | HOH246 |
| B | HOH272 |
| B | HOH273 |
| B | VAL23 |
| B | GLU71 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 226 |
| Chain | Residue |
| A | LYS18 |
| A | ASN19 |
| A | HOH312 |
| B | LYS18 |
| B | ASN19 |
| B | HOH242 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 301 |
| Chain | Residue |
| A | PRO118 |
| A | TRP119 |
| A | HOH352 |
| B | TRP119 |
| B | HOH226 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:30348641, ECO:0007744|PDB:6FOG |
| Chain | Residue | Details |
| A | ARG25 | |
| A | LYS123 | |
| A | THR192 | |
| B | ARG25 | |
| B | LYS123 | |
| B | THR192 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15551868, ECO:0000269|PubMed:30348641, ECO:0007744|PDB:1SAW, ECO:0007744|PDB:6FOG, ECO:0007744|PDB:6FOH |
| Chain | Residue | Details |
| A | GLU71 | |
| A | GLU73 | |
| A | ASP102 | |
| B | GLU71 | |
| B | GLU73 | |
| B | ASP102 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q6AYQ8 |
| Chain | Residue | Details |
| A | SER40 | |
| B | SER40 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q8R0F8 |
| Chain | Residue | Details |
| A | LYS113 | |
| B | LYS113 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: N6-succinyllysine => ECO:0000250|UniProtKB:Q8R0F8 |
| Chain | Residue | Details |
| A | LYS115 | |
| B | LYS115 |
