Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 1 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH295 |
| A | HOH327 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2 |
| Chain | Residue |
| A | HOH490 |
| A | HOH519 |
| A | ASN48 |
| A | ARG66 |
| A | HOH433 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 3 |
| Chain | Residue |
| A | ASN95 |
| A | ASN97 |
| A | THR98 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 4 |
| Chain | Residue |
| A | SER37 |
| A | LYS60 |
| A | ASP165 |
| A | SER166 |
| A | HOH480 |
| A | HOH515 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 5 |
| Chain | Residue |
| A | ARG125 |
| A | TYR217 |
| A | HOH400 |
| A | HOH415 |
| A | HOH416 |
| A | HOH443 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 6 |
| Chain | Residue |
| A | ASN97 |
| A | ARG125 |
| A | GLN204 |
| A | HOH380 |
| A | HOH400 |
| A | HOH403 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 7 |
| Chain | Residue |
| A | GLY96 |
| A | ASN97 |
| A | ARG125 |
| A | SER127 |
| A | GLN204 |
| A | GLN210 |
| A | HOH385 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A 8 |
| Chain | Residue |
| A | ASN34 |
| A | GLY38 |
| A | SER39 |
| A | HIS40 |
| A | ILE73 |
| A | ASP74 |
| A | HOH516 |
| A | HOH519 |
| A | HOH520 |
| A | HOH521 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 9 |
| Chain | Residue |
| A | ILE47 |
| A | ASN48 |
| A | LEU123 |
| A | TYR217 |
| A | HOH431 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 10 |
| Chain | Residue |
| A | HIS91 |
| A | ASN101 |
| A | SER149 |
| A | ASN179 |
| A | ASN233 |
| A | HOH309 |
| A | HOH344 |
| A | HOH438 |
| site_id | BC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE DYB A 11 |
| Chain | Residue |
| A | HIS57 |
| A | ASP189 |
| A | SER190 |
| A | CYS191 |
| A | GLY193 |
| A | SER195 |
| A | HOH283 |
| A | HOH303 |
| A | HOH381 |
| A | HOH383 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Required for specificity => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP189 | |
