1S60

Aminoglycoside N-Acetyltransferase AAC(6')-Iy in Complex with CoA and N-terminal His(6)-tag (crystal form 2)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006084	biological_process	acetyl-CoA metabolic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0042803	molecular_function	protein homodimerization activity
A	0046677	biological_process	response to antibiotic
A	0047663	molecular_function	aminoglycoside 6'-N-acetyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 800

Chain	Residue
A	THR116
A	SER117
A	ASN120
A	COA600

---

site_id	AC2
Number of Residues	19
Details	BINDING SITE FOR RESIDUE COA A 600

Chain	Residue
A	GLN89
A	ARG90
A	GLY91
A	VAL92
A	ALA93
A	LYS94
A	ASN120
A	ILE122
A	SER123
A	LYS125
A	VAL126
A	ALA129
A	LEU130
A	SO4800
A	GLY80
A	ILE81
A	PHE82
A	VAL83
A	ARG88

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	144
Details	Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15123251","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	13
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15123251","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18095712","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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