1S5K
Aminoglycoside N-Acetyltransferase AAC(6')-Iy in Complex with CoA and N-terminal His(6)-tag (crystal form 1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0047663 | molecular_function | aminoglycoside 6'-N-acetyltransferase activity |
| B | 0006084 | biological_process | acetyl-CoA metabolic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0047663 | molecular_function | aminoglycoside 6'-N-acetyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 800 |
| Chain | Residue |
| A | THR116 |
| A | SER117 |
| A | ASN120 |
| A | COA600 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 801 |
| Chain | Residue |
| B | THR116 |
| B | SER117 |
| B | ASN120 |
| B | COA601 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE COA A 600 |
| Chain | Residue |
| A | PHE82 |
| A | VAL83 |
| A | ARG88 |
| A | GLN89 |
| A | ARG90 |
| A | GLY91 |
| A | VAL92 |
| A | ALA93 |
| A | LYS94 |
| A | ASN120 |
| A | ILE122 |
| A | LYS125 |
| A | VAL126 |
| A | ALA129 |
| A | SO4800 |
| A | ILE81 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE COA B 601 |
| Chain | Residue |
| B | LEU21 |
| B | ILE81 |
| B | PHE82 |
| B | VAL83 |
| B | ARG88 |
| B | GLN89 |
| B | ARG90 |
| B | GLY91 |
| B | VAL92 |
| B | ALA93 |
| B | LYS94 |
| B | ASN120 |
| B | ILE122 |
| B | SER123 |
| B | VAL126 |
| B | ALA129 |
| B | SO4801 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 144 |
| Details | Domain: {"description":"N-acetyltransferase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00532","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15123251","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 25 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15123251","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18095712","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
