1S5H

Potassium Channel Kcsa-Fab Complex T75C mutant in K+

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0006813	biological_process	potassium ion transport
C	0008076	cellular_component	voltage-gated potassium channel complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE K C 401

Chain	Residue
C	GLY77
C	K402
C	K402
C	K402
C	GLY77
C	GLY77
C	GLY77
C	TYR78
C	TYR78
C	TYR78
C	TYR78
C	K402

---

site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE K C 402

Chain	Residue
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	GLY77
C	GLY77
C	GLY77
C	GLY77
C	K401
C	K401
C	K401
C	K401
C	K403
C	K403
C	K403
C	K403

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE K C 403

Chain	Residue
C	CYS75
C	CYS75
C	CYS75
C	CYS75
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	K402
C	K402
C	K402
C	K402

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K C 406

Chain	Residue
C	K407
C	K407
C	K407
C	K407

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE K C 407

Chain	Residue
C	K406
C	K406
C	K406
C	K406

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE DGA C 301

Chain	Residue
C	LEU86
C	ARG89
C	HOH438

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE F09 B 302

Chain	Residue
B	ARG57

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
A	TYR192-HIS198

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Intramembrane: {"description":"Helical; Pore-forming","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	7
Details	Intramembrane: {"description":"Pore-forming","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	5
Details	Motif: {"description":"Selectivity filter"}

Chain

Residue

Details

---