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1S59

Structure of nucleoside diphosphate kinase 2 with bound dGTP from Arabidopsis

Functional Information from GO Data
ChainGOidnamespacecontents
A0004550molecular_functionnucleoside diphosphate kinase activity
A0006183biological_processGTP biosynthetic process
A0006228biological_processUTP biosynthetic process
A0006241biological_processCTP biosynthetic process
B0004550molecular_functionnucleoside diphosphate kinase activity
B0006183biological_processGTP biosynthetic process
B0006228biological_processUTP biosynthetic process
B0006241biological_processCTP biosynthetic process
C0004550molecular_functionnucleoside diphosphate kinase activity
C0006183biological_processGTP biosynthetic process
C0006228biological_processUTP biosynthetic process
C0006241biological_processCTP biosynthetic process
D0004550molecular_functionnucleoside diphosphate kinase activity
D0006183biological_processGTP biosynthetic process
D0006228biological_processUTP biosynthetic process
D0006241biological_processCTP biosynthetic process
E0004550molecular_functionnucleoside diphosphate kinase activity
E0006183biological_processGTP biosynthetic process
E0006228biological_processUTP biosynthetic process
E0006241biological_processCTP biosynthetic process
F0004550molecular_functionnucleoside diphosphate kinase activity
F0006183biological_processGTP biosynthetic process
F0006228biological_processUTP biosynthetic process
F0006241biological_processCTP biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE DGI A 1101
ChainResidue
APHE139
AARG167
ATHR173
AARG184
AASN194
AHOH1137
CGLU231

site_idAC2
Number of Residues13
DetailsBINDING SITE FOR RESIDUE DGT C 1102
ChainResidue
CTYR131
CLEU134
CPHE139
CTHR173
CARG184
CTHR191
CASN194
CVAL196
CHIS197
CGLY198
CHOH1117
BGLU231
CLYS91

Functional Information from PROSITE/UniProt
site_idPS00469
Number of Residues9
DetailsNDPK Nucleoside diphosphate kinase (NDPK) active site signature. NivHGSDSP
ChainResidueDetails
AASN194-PRO202

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsActive site: {"description":"Pros-phosphohistidine intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues36
DetailsBinding site: {}
ChainResidueDetails

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
ALYS91
AASN194

site_idCSA10
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
DTYR131
DLYS91

site_idCSA11
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
ETYR131
ELYS91

site_idCSA12
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
FTYR131
FLYS91

site_idCSA2
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
BLYS91
BASN194

site_idCSA3
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
CLYS91
CASN194

site_idCSA4
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
DLYS91
DASN194

site_idCSA5
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
ELYS91
EASN194

site_idCSA6
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
FLYS91
FASN194

site_idCSA7
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
ATYR131
ALYS91

site_idCSA8
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
BTYR131
BLYS91

site_idCSA9
Number of Residues2
DetailsAnnotated By Reference To The Literature 1nsp
ChainResidueDetails
CTYR131
CLYS91

246704

PDB entries from 2025-12-24

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