1S4X

NMR Structure of the integrin B3 cytoplasmic domain in DPC micelles

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005178	molecular_function	integrin binding
A	0007155	biological_process	cell adhesion
A	0007229	biological_process	integrin-mediated signaling pathway
A	0008305	cellular_component	integrin complex
A	0070527	biological_process	platelet aggregation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	46
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Motif: {"description":"LIR","evidences":[{"source":"PubMed","id":"33436497","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"33436498","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"O54890","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"19141530","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18088087","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine; by PDPK1 and PKB/AKT1; in vitro","evidences":[{"source":"PubMed","id":"10896934","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"8631894","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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