Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
A | 0004523 | molecular_function | RNA-DNA hybrid ribonuclease activity |
A | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
B | 0003964 | molecular_function | RNA-directed DNA polymerase activity |
B | 0006278 | biological_process | RNA-templated DNA biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE TNK A 999 |
Chain | Residue |
A | ILE100 |
A | LEU234 |
A | HIS235 |
A | PRO236 |
A | TYR318 |
A | LYS101 |
A | LYS102 |
A | LYS103 |
A | VAL106 |
A | TYR181 |
A | TYR188 |
A | GLY190 |
A | TRP229 |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
B | HIS235-TRP252 | |
Chain | Residue | Details |
B | ASP256-GLY273 | |
Chain | Residue | Details |
B | ARG358 | |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | SITE: Cis/trans isomerization of proline peptide bond; by human PPIA/CYPA |
Chain | Residue | Details |
B | LYS66 | |
site_id | SWS_FT_FI5 |
Number of Residues | 4 |
Details | SITE: Cleavage; by viral protease => ECO:0000250 |
Chain | Residue | Details |
B | HIS208 | |
B | GLN222 | |
B | GLY285 | |
B | GLU432 | |
site_id | SWS_FT_FI6 |
Number of Residues | 3 |
Details | SITE: Cleavage; by viral protease => ECO:0000255 |
Chain | Residue | Details |
B | LYS238 | |
B | TYR271 | |
B | ARG277 | |
A | GLU432 | |
Chain | Residue | Details |
B | GLY333 | |
A | TYR271 | |
A | ARG277 | |
Chain | Residue | Details |
A | GLY333 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 175 |
Chain | Residue | Details |
B | ARG358 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
B | GLY359 | electrostatic stabiliser, transition state stabiliser |
B | ALA360 | electrostatic stabiliser, hydrogen bond donor |