1RZR
crystal structure of transcriptional regulator-phosphoprotein-DNA complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0000976 | molecular_function | transcription cis-regulatory region binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| D | 0000976 | molecular_function | transcription cis-regulatory region binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003700 | molecular_function | DNA-binding transcription factor activity |
| D | 0006355 | biological_process | regulation of DNA-templated transcription |
| G | 0000976 | molecular_function | transcription cis-regulatory region binding |
| G | 0003677 | molecular_function | DNA binding |
| G | 0003700 | molecular_function | DNA-binding transcription factor activity |
| G | 0006355 | biological_process | regulation of DNA-templated transcription |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
| S | 0005737 | cellular_component | cytoplasm |
| S | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
| T | 0005737 | cellular_component | cytoplasm |
| T | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
| Y | 0005737 | cellular_component | cytoplasm |
| Y | 0009401 | biological_process | phosphoenolpyruvate-dependent sugar phosphotransferase system |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 599 |
| Chain | Residue |
| A | THR87 |
| A | TYR91 |
| A | ASN92 |
| D | ASN111 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 946 |
| Chain | Residue |
| A | HIS107 |
| A | ASN111 |
| D | THR87 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 947 |
| Chain | Residue |
| G | THR87 |
| G | TYR91 |
| G | ASN92 |
| C | ASN111 |
| C | HOH960 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 C 846 |
| Chain | Residue |
| C | THR87 |
| C | LYS90 |
| C | TYR91 |
| C | ASN92 |
| G | SER96 |
| G | HIS107 |
| G | ASN111 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 G 646 |
| Chain | Residue |
| G | LYS201 |
| G | ASP213 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 G 647 |
| Chain | Residue |
| G | ARG212 |
| G | ASP213 |
| G | SER214 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 346 |
| Chain | Residue |
| C | SER138 |
| C | VAL140 |
| C | HOH955 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG D 754 |
| Chain | Residue |
| D | ASN101 |
| D | ASP103 |
| D | LYS104 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 704 |
| Chain | Residue |
| A | ASN101 |
| A | ASP103 |
| A | LYS104 |
Functional Information from PROSITE/UniProt
| site_id | PS00356 |
| Number of Residues | 19 |
| Details | HTH_LACI_1 LacI-type HTH domain signature. IyDVAreAsVSmaTVsrVV |
| Chain | Residue | Details |
| D | ILE5-VAL23 | |
| G | ILE5-VAL23 |
| site_id | PS00369 |
| Number of Residues | 8 |
| Details | PTS_HPR_HIS PTS HPR domain histidine phosphorylation site signature. GIHARPAT |
| Chain | Residue | Details |
| T | GLY13-THR20 |
| site_id | PS00589 |
| Number of Residues | 16 |
| Details | PTS_HPR_SER PTS HPR domain serine phosphorylation site signature. GKtVNlKSIMGVMsLG |
| Chain | Residue | Details |
| T | GLY39-GLY54 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Pros-phosphohistidine intermediate => ECO:0000255|PROSITE-ProRule:PRU00681 |
| Chain | Residue | Details |
| T | HIS15 | |
| L | HIS15 | |
| Y | HIS15 | |
| S | HIS15 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250 |
| Chain | Residue | Details |
| T | SER12 | |
| L | SER12 | |
| Y | SER12 | |
| S | SER12 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine; by HPrK/P => ECO:0000255|PROSITE-ProRule:PRU00681, ECO:0000269|PubMed:15369672, ECO:0000269|PubMed:17376479 |
| Chain | Residue | Details |
| T | SEP46 | |
| L | SEP46 | |
| Y | SEP46 | |
| S | SEP46 |
