1RZR

crystal structure of transcriptional regulator-phosphoprotein-DNA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
C	0000976	molecular_function	transcription cis-regulatory region binding
C	0003677	molecular_function	DNA binding
C	0003700	molecular_function	DNA-binding transcription factor activity
C	0006351	biological_process	DNA-templated transcription
C	0006355	biological_process	regulation of DNA-templated transcription
D	0000976	molecular_function	transcription cis-regulatory region binding
D	0003677	molecular_function	DNA binding
D	0003700	molecular_function	DNA-binding transcription factor activity
D	0006351	biological_process	DNA-templated transcription
D	0006355	biological_process	regulation of DNA-templated transcription
G	0000976	molecular_function	transcription cis-regulatory region binding
G	0003677	molecular_function	DNA binding
G	0003700	molecular_function	DNA-binding transcription factor activity
G	0006351	biological_process	DNA-templated transcription
G	0006355	biological_process	regulation of DNA-templated transcription
L	0005737	cellular_component	cytoplasm
L	0006351	biological_process	DNA-templated transcription
L	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
S	0005737	cellular_component	cytoplasm
S	0006351	biological_process	DNA-templated transcription
S	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
T	0005737	cellular_component	cytoplasm
T	0006351	biological_process	DNA-templated transcription
T	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y	0005737	cellular_component	cytoplasm
Y	0006351	biological_process	DNA-templated transcription
Y	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 599

Chain	Residue
A	THR87
A	TYR91
A	ASN92
D	ASN111

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 946

Chain	Residue
A	HIS107
A	ASN111
D	THR87

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 C 947

Chain	Residue
G	THR87
G	TYR91
G	ASN92
C	ASN111
C	HOH960

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 C 846

Chain	Residue
C	THR87
C	LYS90
C	TYR91
C	ASN92
G	SER96
G	HIS107
G	ASN111

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 G 646

Chain	Residue
G	LYS201
G	ASP213

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 G 647

Chain	Residue
G	ARG212
G	ASP213
G	SER214

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 346

Chain	Residue
C	SER138
C	VAL140
C	HOH955

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG D 754

Chain	Residue
D	ASN101
D	ASP103
D	LYS104

---

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 704

Chain	Residue
A	ASN101
A	ASP103
A	LYS104

---

Functional Information from PROSITE/UniProt

site_id	PS00356
Number of Residues	19
Details	HTH_LACI_1 LacI-type HTH domain signature. IyDVAreAsVSmaTVsrVV

Chain	Residue	Details
G	ILE5-VAL23
D	ILE5-VAL23

---

site_id	PS00369
Number of Residues	8
Details	PTS_HPR_HIS PTS HPR domain histidine phosphorylation site signature. GIHARPAT

Chain	Residue	Details
T	GLY13-THR20

---

site_id	PS00589
Number of Residues	16
Details	PTS_HPR_SER PTS HPR domain serine phosphorylation site signature. GKtVNlKSIMGVMsLG

Chain	Residue	Details
T	GLY39-GLY54

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Pros-phosphohistidine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00681","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Modified residue: {"description":"Phosphoserine; by HPrK/P","evidences":[{"source":"PROSITE-ProRule","id":"PRU00681","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15369672","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17376479","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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