1RZM
Crystal structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHPS) from Thermotoga maritima complexed with Cd2+, PEP and E4P
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016832 | molecular_function | aldehyde-lyase activity |
| B | 0003849 | molecular_function | 3-deoxy-7-phosphoheptulonate synthase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016832 | molecular_function | aldehyde-lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 8001 |
| Chain | Residue |
| A | CYS102 |
| A | HIS272 |
| A | GLU298 |
| A | ASP309 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CD B 9001 |
| Chain | Residue |
| B | CYS102 |
| B | HIS272 |
| B | GLU298 |
| B | ASP309 |
| B | E4P9003 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 9009 |
| Chain | Residue |
| A | HIS115 |
| A | GLU119 |
| B | HIS115 |
| B | GLU119 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PEP A 8002 |
| Chain | Residue |
| A | ARG126 |
| A | LYS131 |
| A | GLN182 |
| A | GLY184 |
| A | ALA185 |
| A | ARG186 |
| A | LYS207 |
| A | ARG237 |
| A | HIS272 |
| A | E4P8003 |
| A | HOH8015 |
| A | HOH8018 |
| A | HOH8061 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PEP B 9002 |
| Chain | Residue |
| B | ARG126 |
| B | LYS131 |
| B | GLN182 |
| B | GLY184 |
| B | ALA185 |
| B | ARG186 |
| B | LYS207 |
| B | ARG237 |
| B | HIS272 |
| B | E4P9003 |
| B | HOH9023 |
| B | HOH9036 |
| B | HOH9038 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE E4P A 8003 |
| Chain | Residue |
| A | LYS131 |
| A | PRO132 |
| A | ARG133 |
| A | THR134 |
| A | ARG186 |
| A | SER308 |
| A | ASP309 |
| A | PEP8002 |
| A | HOH8025 |
| A | HOH8055 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE E4P B 9003 |
| Chain | Residue |
| B | CYS102 |
| B | LYS131 |
| B | PRO132 |
| B | ARG133 |
| B | THR134 |
| B | ARG186 |
| B | SER308 |
| B | ASP309 |
| B | CD9001 |
| B | PEP9002 |
| B | HOH9049 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| A | HIS272 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1q3n |
| Chain | Residue | Details |
| B | HIS272 |
