Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1RZ1

Reduced flavin reductase PheA2 in complex with NAD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0006208	biological_process	pyrimidine nucleobase catabolic process
A	0010181	molecular_function	FMN binding
A	0016646	molecular_function	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
A	0042602	molecular_function	riboflavin reductase (NADPH) activity
B	0000166	molecular_function	nucleotide binding
B	0006208	biological_process	pyrimidine nucleobase catabolic process
B	0010181	molecular_function	FMN binding
B	0016646	molecular_function	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
B	0042602	molecular_function	riboflavin reductase (NADPH) activity
C	0000166	molecular_function	nucleotide binding
C	0006208	biological_process	pyrimidine nucleobase catabolic process
C	0010181	molecular_function	FMN binding
C	0016646	molecular_function	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
C	0042602	molecular_function	riboflavin reductase (NADPH) activity
D	0000166	molecular_function	nucleotide binding
D	0006208	biological_process	pyrimidine nucleobase catabolic process
D	0010181	molecular_function	FMN binding
D	0016646	molecular_function	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
D	0042602	molecular_function	riboflavin reductase (NADPH) activity
E	0000166	molecular_function	nucleotide binding
E	0006208	biological_process	pyrimidine nucleobase catabolic process
E	0010181	molecular_function	FMN binding
E	0016646	molecular_function	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
E	0042602	molecular_function	riboflavin reductase (NADPH) activity
F	0000166	molecular_function	nucleotide binding
F	0006208	biological_process	pyrimidine nucleobase catabolic process
F	0010181	molecular_function	FMN binding
F	0016646	molecular_function	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
F	0042602	molecular_function	riboflavin reductase (NADPH) activity
G	0000166	molecular_function	nucleotide binding
G	0006208	biological_process	pyrimidine nucleobase catabolic process
G	0010181	molecular_function	FMN binding
G	0016646	molecular_function	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
G	0042602	molecular_function	riboflavin reductase (NADPH) activity
H	0000166	molecular_function	nucleotide binding
H	0006208	biological_process	pyrimidine nucleobase catabolic process
H	0010181	molecular_function	FMN binding
H	0016646	molecular_function	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
H	0042602	molecular_function	riboflavin reductase (NADPH) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	BINDING SITE FOR RESIDUE FAD A 1200

Chain	Residue
A	VAL28
A	GLY51
A	ALA54
A	LYS55
A	MSE56
A	ASN81
A	PHE82
A	ALA83
A	GLY84
A	PRO89
A	VAL90
A	GLY30
A	NAD1201
A	HOH1218
A	HOH1241
A	HOH1245
A	HOH1251
A	MSE31
A	THR32
A	ALA33
A	ASN34
A	ALA35
A	SER49
A	ILE50

site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE NAD A 1201

Chain	Residue
A	ARG7
A	MSE10
A	GLY11
A	ASN34
A	ALA35
A	HIS123
A	PHE143
A	FAD1200
A	HOH1206
A	HOH1211
A	HOH1221
A	HOH1243
B	SER38

site_id	AC3
Number of Residues	21
Details	BINDING SITE FOR RESIDUE FAD B 2200

Chain	Residue
B	VAL28
B	GLY30
B	MSE31
B	THR32
B	ALA33
B	ASN34
B	ALA35
B	SER49
B	ILE50
B	GLY51
B	ALA54
B	LYS55
B	MSE56
B	ASN81
B	PHE82
B	ALA83
B	GLY84
B	PRO89
B	VAL90
B	NAD2201
B	HOH2207

site_id	AC4
Number of Residues	13
Details	BINDING SITE FOR RESIDUE NAD B 2201

Chain	Residue
A	SER38
A	HOH1205
B	ARG7
B	MSE10
B	GLY11
B	ASN34
B	ALA35
B	HIS123
B	PHE143
B	FAD2200
B	HOH2216
B	HOH2246
B	HOH2247

site_id	AC5
Number of Residues	22
Details	BINDING SITE FOR RESIDUE FAD C 3200

Chain	Residue
C	VAL28
C	GLY30
C	MSE31
C	THR32
C	ALA33
C	ASN34
C	ALA35
C	SER49
C	ILE50
C	GLY51
C	ALA54
C	LYS55
C	MSE56
C	ASN81
C	PHE82
C	ALA83
C	GLY84
C	PRO89
C	VAL90
C	NAD3201
C	HOH3221
C	HOH3247

site_id	AC6
Number of Residues	18
Details	BINDING SITE FOR RESIDUE NAD C 3201

Chain	Residue
C	PHE143
C	FAD3200
C	HOH3206
C	HOH3231
C	HOH3232
C	HOH3233
C	HOH3235
C	HOH3239
C	HOH3248
C	HOH3251
D	SER38
D	VAL39
C	ARG7
C	MSE10
C	GLY11
C	ASN34
C	ALA35
C	HIS123

site_id	AC7
Number of Residues	21
Details	BINDING SITE FOR RESIDUE FAD D 4200

Chain	Residue
D	VAL28
D	GLY30
D	MSE31
D	THR32
D	ALA33
D	ASN34
D	ALA35
D	SER49
D	GLY51
D	ALA54
D	LYS55
D	MSE56
D	ASN81
D	PHE82
D	ALA83
D	GLY84
D	PRO89
D	VAL90
D	NAD4201
D	HOH4204
D	HOH4243

site_id	AC8
Number of Residues	17
Details	BINDING SITE FOR RESIDUE NAD D 4201

Chain	Residue
C	SER38
C	VAL39
C	HOH3217
D	ARG7
D	MSE10
D	GLY11
D	ASN34
D	ALA35
D	HIS123
D	PHE143
D	FAD4200
D	HOH4210
D	HOH4215
D	HOH4223
D	HOH4227
D	HOH4239
D	HOH4246

site_id	AC9
Number of Residues	22
Details	BINDING SITE FOR RESIDUE FAD E 5200

Chain	Residue
E	VAL28
E	GLY30
E	MSE31
E	THR32
E	ALA33
E	ASN34
E	ALA35
E	SER49
E	GLY51
E	ALA54
E	LYS55
E	MSE56
E	ASN81
E	PHE82
E	ALA83
E	GLY84
E	PRO89
E	VAL90
E	NAD5201
E	HOH5209
E	HOH5214
E	HOH5217

site_id	BC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE NAD E 5201

Chain	Residue
E	ARG7
E	MSE10
E	GLY11
E	ASN34
E	ALA35
E	HIS123
E	PHE143
E	FAD5200
E	HOH5208
E	HOH5225
F	SER38
F	HOH6207

site_id	BC2
Number of Residues	21
Details	BINDING SITE FOR RESIDUE FAD F 6200

Chain	Residue
F	VAL28
F	GLY30
F	MSE31
F	THR32
F	ALA33
F	ASN34
F	ALA35
F	SER49
F	GLY51
F	ALA54
F	LYS55
F	MSE56
F	ASN81
F	PHE82
F	ALA83
F	GLY84
F	PRO89
F	VAL90
F	NAD6201
F	HOH6206
F	HOH6227

site_id	BC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE NAD F 6201

Chain	Residue
E	SER38
E	VAL39
F	ARG7
F	MSE10
F	GLY11
F	ASN34
F	ALA35
F	HIS123
F	PHE143
F	FAD6200
F	HOH6205
F	HOH6210
F	HOH6212
F	HOH6242

site_id	BC4
Number of Residues	23
Details	BINDING SITE FOR RESIDUE FAD G 7200

Chain	Residue
G	VAL28
G	GLY30
G	MSE31
G	THR32
G	ALA33
G	ASN34
G	ALA35
G	SER49
G	ILE50
G	GLY51
G	ALA54
G	LYS55
G	MSE56
G	ASN81
G	PHE82
G	ALA83
G	GLY84
G	PRO89
G	VAL90
G	NAD7201
G	HOH7208
G	HOH7230
G	HOH7245

site_id	BC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE NAD G 7201

Chain	Residue
G	ARG7
G	MSE10
G	GLY11
G	ASN34
G	ALA35
G	HIS123
G	PHE143
G	FAD7200
G	HOH7214
G	HOH7216
G	HOH7218
G	HOH7227
H	SER38
H	HOH8203

site_id	BC6
Number of Residues	21
Details	BINDING SITE FOR RESIDUE FAD H 8200

Chain	Residue
H	VAL28
H	GLY30
H	MSE31
H	THR32
H	ALA33
H	ASN34
H	ALA35
H	SER49
H	ILE50
H	GLY51
H	ALA54
H	LYS55
H	MSE56
H	ASN81
H	PHE82
H	ALA83
H	GLY84
H	PRO89
H	VAL90
H	NAD8201
H	HOH8228

site_id	BC7
Number of Residues	13
Details	BINDING SITE FOR RESIDUE NAD H 8201

Chain	Residue
G	SER38
G	HOH7203
H	ARG7
H	MSE10
H	GLY11
H	ASN34
H	ALA35
H	HIS123
H	PHE143
H	FAD8200
H	HOH8229
H	HOH8241
H	HOH8243

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)