1RZ1
Reduced flavin reductase PheA2 in complex with NAD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016646 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| A | 0042602 | molecular_function | riboflavin reductase (NADPH) activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016646 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| B | 0042602 | molecular_function | riboflavin reductase (NADPH) activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| C | 0010181 | molecular_function | FMN binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016646 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| C | 0042602 | molecular_function | riboflavin reductase (NADPH) activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| D | 0010181 | molecular_function | FMN binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016646 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| D | 0042602 | molecular_function | riboflavin reductase (NADPH) activity |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| E | 0010181 | molecular_function | FMN binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016646 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| E | 0042602 | molecular_function | riboflavin reductase (NADPH) activity |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| F | 0010181 | molecular_function | FMN binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016646 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| F | 0042602 | molecular_function | riboflavin reductase (NADPH) activity |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| G | 0010181 | molecular_function | FMN binding |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016646 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| G | 0042602 | molecular_function | riboflavin reductase (NADPH) activity |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0006208 | biological_process | pyrimidine nucleobase catabolic process |
| H | 0010181 | molecular_function | FMN binding |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016646 | molecular_function | oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor |
| H | 0042602 | molecular_function | riboflavin reductase (NADPH) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE FAD A 1200 |
| Chain | Residue |
| A | VAL28 |
| A | GLY51 |
| A | ALA54 |
| A | LYS55 |
| A | MSE56 |
| A | ASN81 |
| A | PHE82 |
| A | ALA83 |
| A | GLY84 |
| A | PRO89 |
| A | VAL90 |
| A | GLY30 |
| A | NAD1201 |
| A | HOH1218 |
| A | HOH1241 |
| A | HOH1245 |
| A | HOH1251 |
| A | MSE31 |
| A | THR32 |
| A | ALA33 |
| A | ASN34 |
| A | ALA35 |
| A | SER49 |
| A | ILE50 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE NAD A 1201 |
| Chain | Residue |
| A | ARG7 |
| A | MSE10 |
| A | GLY11 |
| A | ASN34 |
| A | ALA35 |
| A | HIS123 |
| A | PHE143 |
| A | FAD1200 |
| A | HOH1206 |
| A | HOH1211 |
| A | HOH1221 |
| A | HOH1243 |
| B | SER38 |
| site_id | AC3 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FAD B 2200 |
| Chain | Residue |
| B | VAL28 |
| B | GLY30 |
| B | MSE31 |
| B | THR32 |
| B | ALA33 |
| B | ASN34 |
| B | ALA35 |
| B | SER49 |
| B | ILE50 |
| B | GLY51 |
| B | ALA54 |
| B | LYS55 |
| B | MSE56 |
| B | ASN81 |
| B | PHE82 |
| B | ALA83 |
| B | GLY84 |
| B | PRO89 |
| B | VAL90 |
| B | NAD2201 |
| B | HOH2207 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE NAD B 2201 |
| Chain | Residue |
| A | SER38 |
| A | HOH1205 |
| B | ARG7 |
| B | MSE10 |
| B | GLY11 |
| B | ASN34 |
| B | ALA35 |
| B | HIS123 |
| B | PHE143 |
| B | FAD2200 |
| B | HOH2216 |
| B | HOH2246 |
| B | HOH2247 |
| site_id | AC5 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE FAD C 3200 |
| Chain | Residue |
| C | VAL28 |
| C | GLY30 |
| C | MSE31 |
| C | THR32 |
| C | ALA33 |
| C | ASN34 |
| C | ALA35 |
| C | SER49 |
| C | ILE50 |
| C | GLY51 |
| C | ALA54 |
| C | LYS55 |
| C | MSE56 |
| C | ASN81 |
| C | PHE82 |
| C | ALA83 |
| C | GLY84 |
| C | PRO89 |
| C | VAL90 |
| C | NAD3201 |
| C | HOH3221 |
| C | HOH3247 |
| site_id | AC6 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE NAD C 3201 |
| Chain | Residue |
| C | PHE143 |
| C | FAD3200 |
| C | HOH3206 |
| C | HOH3231 |
| C | HOH3232 |
| C | HOH3233 |
| C | HOH3235 |
| C | HOH3239 |
| C | HOH3248 |
| C | HOH3251 |
| D | SER38 |
| D | VAL39 |
| C | ARG7 |
| C | MSE10 |
| C | GLY11 |
| C | ASN34 |
| C | ALA35 |
| C | HIS123 |
| site_id | AC7 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FAD D 4200 |
| Chain | Residue |
| D | VAL28 |
| D | GLY30 |
| D | MSE31 |
| D | THR32 |
| D | ALA33 |
| D | ASN34 |
| D | ALA35 |
| D | SER49 |
| D | GLY51 |
| D | ALA54 |
| D | LYS55 |
| D | MSE56 |
| D | ASN81 |
| D | PHE82 |
| D | ALA83 |
| D | GLY84 |
| D | PRO89 |
| D | VAL90 |
| D | NAD4201 |
| D | HOH4204 |
| D | HOH4243 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NAD D 4201 |
| Chain | Residue |
| C | SER38 |
| C | VAL39 |
| C | HOH3217 |
| D | ARG7 |
| D | MSE10 |
| D | GLY11 |
| D | ASN34 |
| D | ALA35 |
| D | HIS123 |
| D | PHE143 |
| D | FAD4200 |
| D | HOH4210 |
| D | HOH4215 |
| D | HOH4223 |
| D | HOH4227 |
| D | HOH4239 |
| D | HOH4246 |
| site_id | AC9 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE FAD E 5200 |
| Chain | Residue |
| E | VAL28 |
| E | GLY30 |
| E | MSE31 |
| E | THR32 |
| E | ALA33 |
| E | ASN34 |
| E | ALA35 |
| E | SER49 |
| E | GLY51 |
| E | ALA54 |
| E | LYS55 |
| E | MSE56 |
| E | ASN81 |
| E | PHE82 |
| E | ALA83 |
| E | GLY84 |
| E | PRO89 |
| E | VAL90 |
| E | NAD5201 |
| E | HOH5209 |
| E | HOH5214 |
| E | HOH5217 |
| site_id | BC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE NAD E 5201 |
| Chain | Residue |
| E | ARG7 |
| E | MSE10 |
| E | GLY11 |
| E | ASN34 |
| E | ALA35 |
| E | HIS123 |
| E | PHE143 |
| E | FAD5200 |
| E | HOH5208 |
| E | HOH5225 |
| F | SER38 |
| F | HOH6207 |
| site_id | BC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FAD F 6200 |
| Chain | Residue |
| F | VAL28 |
| F | GLY30 |
| F | MSE31 |
| F | THR32 |
| F | ALA33 |
| F | ASN34 |
| F | ALA35 |
| F | SER49 |
| F | GLY51 |
| F | ALA54 |
| F | LYS55 |
| F | MSE56 |
| F | ASN81 |
| F | PHE82 |
| F | ALA83 |
| F | GLY84 |
| F | PRO89 |
| F | VAL90 |
| F | NAD6201 |
| F | HOH6206 |
| F | HOH6227 |
| site_id | BC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE NAD F 6201 |
| Chain | Residue |
| E | SER38 |
| E | VAL39 |
| F | ARG7 |
| F | MSE10 |
| F | GLY11 |
| F | ASN34 |
| F | ALA35 |
| F | HIS123 |
| F | PHE143 |
| F | FAD6200 |
| F | HOH6205 |
| F | HOH6210 |
| F | HOH6212 |
| F | HOH6242 |
| site_id | BC4 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE FAD G 7200 |
| Chain | Residue |
| G | VAL28 |
| G | GLY30 |
| G | MSE31 |
| G | THR32 |
| G | ALA33 |
| G | ASN34 |
| G | ALA35 |
| G | SER49 |
| G | ILE50 |
| G | GLY51 |
| G | ALA54 |
| G | LYS55 |
| G | MSE56 |
| G | ASN81 |
| G | PHE82 |
| G | ALA83 |
| G | GLY84 |
| G | PRO89 |
| G | VAL90 |
| G | NAD7201 |
| G | HOH7208 |
| G | HOH7230 |
| G | HOH7245 |
| site_id | BC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE NAD G 7201 |
| Chain | Residue |
| G | ARG7 |
| G | MSE10 |
| G | GLY11 |
| G | ASN34 |
| G | ALA35 |
| G | HIS123 |
| G | PHE143 |
| G | FAD7200 |
| G | HOH7214 |
| G | HOH7216 |
| G | HOH7218 |
| G | HOH7227 |
| H | SER38 |
| H | HOH8203 |
| site_id | BC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FAD H 8200 |
| Chain | Residue |
| H | VAL28 |
| H | GLY30 |
| H | MSE31 |
| H | THR32 |
| H | ALA33 |
| H | ASN34 |
| H | ALA35 |
| H | SER49 |
| H | ILE50 |
| H | GLY51 |
| H | ALA54 |
| H | LYS55 |
| H | MSE56 |
| H | ASN81 |
| H | PHE82 |
| H | ALA83 |
| H | GLY84 |
| H | PRO89 |
| H | VAL90 |
| H | NAD8201 |
| H | HOH8228 |
| site_id | BC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE NAD H 8201 |
| Chain | Residue |
| G | SER38 |
| G | HOH7203 |
| H | ARG7 |
| H | MSE10 |
| H | GLY11 |
| H | ASN34 |
| H | ALA35 |
| H | HIS123 |
| H | PHE143 |
| H | FAD8200 |
| H | HOH8229 |
| H | HOH8241 |
| H | HOH8243 |
