1RUM

Crystal structure (F) of H2O2-soaked cationic cyclization antibody 4C6 fab at pH 8.5 with a data set collected at SSRL beamline 9-1.

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0019814	cellular_component	immunoglobulin complex
L	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE BEZ H 1601

Chain	Residue
H	ALA34
H	ASN35
H	LEU95
H	LEU96
H	PRO230
L	TRP89
L	GLY91

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GOL H 1611

Chain	Residue
H	VAL177
H	THR186
H	LEU187
H	SER188
H	HOH1781
L	SER162
L	SER176
L	THR178
L	HOH258
H	PHE174
H	PRO175

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site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL H 1612

Chain	Residue
H	VAL12
H	GLN16
H	SER17
H	ASP32
H	TYR53
H	HOH1617
H	HOH1639
H	HOH1675
H	HOH1930

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL H 1613

Chain	Residue
H	SER120
H	VAL121
H	TYR122
H	SER215
H	VAL219
H	LYS221
H	HOH1664
H	HOH1764
L	GLU123

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	92
Details	Domain: {"description":"Ig-like 1"}

Chain

Residue

Details

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