1RUK

Crystal structure (C) of native cationic cyclization antibody 4C6 fab at pH 4.6 with a data set collected at SSRL beamline 9-1

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT L 611

Chain	Residue
H	LEU95
H	TRP103
L	ASN34
L	LEU36
L	HOH630
L	HOH776

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE BEZ H 601

Chain	Residue
H	LEU96
H	PRO230
L	TRP89
L	GLY91
H	ALA34
H	ASN35
H	LEU95

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site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL H 621

Chain	Residue
H	PHE174
H	PRO175
H	THR186
H	LEU187
H	SER188
H	HOH660
H	HOH743
L	SER162
L	SER176
L	THR178

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL H 622

Chain	Residue
H	GLN16
H	SER17
H	ASP32
H	TYR53
H	HOH636
H	HOH642

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site_id	AC5
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL H 623

Chain	Residue
H	SER120
H	VAL121
H	SER215
H	VAL219
H	LYS221
H	HOH694
H	HOH721
L	GLU123

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site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL H 624

Chain	Residue
H	ARG71
H	ASP72
H	THR73
H	HOH655
L	LYS53
L	LEU54

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
L	TYR192-HIS198

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